Oculocutaneous Albinism is an inherited autosomal recessive condition caused by a mutation in the tyrosinase (TYR) gene. A male and female who are phenotypically normal, discover through genetic testing that they are both carriers of a TYR mutant allele. What is the probability that their first child will be biologically male and have Oculocutaneous Albinism? Select one: a. 1/8 b. 3/4 c. 1/4 d. 1/16 e. 1/2

Q: Please consider the following pedigree. Assume that people who marry in to the family do not carry…

A: Pedigrees are interconnected diagrams to study and trace the particular trait over a few generations…

Q: One parent with the Achondroplasia phenotype and a normal parent have 2 children. Both children have…

A: Achondroplasia is a type of osteochondrodysplasia in which the cartilage at the ends of the limb…

Q: The allele for albinism is recessive to the allele for normal skin pigmentation. All individuals who…

A: An inherited disorder that presents with little or no melanin production, which results in either…

Q: Hemophilia is a disease caused by a gene found on the X chromosome. Therefore, it is a sex-linked…

A: If the woman  gets the X chromosome with the hemophilia gene, she will have hemophilia . A man who…

Q: Marfan’s syndrome is an example of pleiotrophy where individuals with a copy of the dominant allele…

A: It is an inherited disorder that  affects the connective tissues of the body. It is  caused by a…

Q: Galactosemia is an autosomal recessive human disease that is treatable by restricting lactose and…

A: Let,  G - allele for normal galactosemia gene g - allele for recessive galactosemia allele.  Since,…

Q: Hemophilia is caused by an X-linked recessive mutation in humans. If a woman whose paternal uncle…

A: In the disease called “haemophilia”, if a wound is created, the blood does not clot normally. This…

Q: Colorblindness is inherited as an X-linked recessive trait while pattern baldness is controlled by…

A: Colourblindness is X linked recessive condition in which recessive allele h is present on X…

Q: Duchenne muscular dystrophy is an inheritable disorder that results in muscle weakness, leading to…

A: Dichenne muscular dystrophy is a Genetic disorder which show X linked recessive inheritance pattern.…

Q: Hemophilia is an X-linked recessive disorder and blood type is autosomal.  If two healthy parents,…

A: Introduction  X linked inheritance is based on the sex chromosome (X chromosome). This inheritance…

Q: A pedigree analysis was performed on the family of a man with schizophrenia. Based on the known…

A: Schizophrenia is a mental disorder wherein the affected individual is unable to interpret reality…

Q: A male dog is a carrier for the autosomal recessive disorders centronuclear myopathy (Y/y) and von…

A: Centronuclear myopathy and von Willebrand disease is an autosomal dominant disease and is a single…

Q: When phenylalanine is converted to phenylpyruvic acid, this molecule accumulates in the body and…

A: For this we will use binomial expression  P = n!/ x! (n-x!) * pxq(n-x)

Q: Hereditary canine spinal muscular atrophy (HCSMA) is a motor neuron disease in Brittany Spaniels.…

A: Hereditary Canine Spinal Muscular Atrophy (HCSMA), a motor neuron disease affecting Brittany…

Q: an unaffected woman who is heterozygous for the x linked allele causing duchenne muscular dystrophy…

A: Inheritance is the process of transmitting the traits from parent to offspring. Traits of an…

Q: Calculate genotypes and phenotypes in monohybrid crosses of traits with non-Mendelian inheritance…

A: The alleles are the alternative forms of a gene that are located on the same locus of a homologous…

Q: Albinism and sickle cell anemia are both autosomal recessive disorders that are expressed only in…

A: Albinism - genotype be A and a.  aa is diseased, Aa is the carrier and AA is not affected.  Sickle…

Q: Albinism is an autosomal recessive condition characterized by absence of melanin pigment from the…

A: Albinism is a group of genetic disorders characterized by a lack of melanin, the pigment that gives…

Q: What is the most likely mode of inheritance for the trait shown in the following pedigree? This…

A: This is an autosomal recessive trait.

Q: In the Bombay phenotype, a homozygous recessive individual hh appears to have blood type O

A: Blood group in human beings is determined by ABO, Rh factor and Bombay phenotype.

Q: Kelly and Sam are both unaffected carriers for two autosomal recessive disorders, PKU (chromosome…

A: Sir Gregor Mendel was a priest and a teacher who did the famous hybridization experiment on garden…

Q: Acatalasia is caused by a rare autosomal recessive gene. In heterozygous condition catalase activity…

A: Acatelasia is a genetically inherited disorder that causes lowering or absence of production of the…

Q: Sickle cell anemia is inherited as an autosomal recessive condition. It also exhibits incomplete…

A: Sickle cell anemia (SCA) is a genetic disorder that occurs when an individual has two homozygous…

Q: Cystic Fibrosis is an autosomal recessive disorder. A couple are both carriers of the recessive…

A: Cystic fibrosis is an inherited illness which affects the lungs and digestive system. The body…

Q: Piebaldism is a skin condition that causes an infant to be born with white birthmarks due to a…

A: It is an autosomal dominant genetic disorder. It is mainly due to the absence of melanocytes of the…

Q: An X-linked dominant allele contro eceptor mutation that is responsi aldness (MPB). A father who sho…

A: X related qualities are traits that are found on the X chromosome. There are Gerenally well known to…

Q: Below is a pedigree chart for a family that has a history of Alkaptonuria.   Individuals infected…

A: Pedigree analysis is a method to identify the inheritance of a genetic trait across generations.…

Q: A normal female and a male with sickle cell anemi and three with sickle cell anemia. (iii) (iv) Two…

A: Sickle cell anemia and sickle cell disease is an inherited disorder that occurs due to a faulty…

Q: Consider a situation where you have a parental cross with the mother and father phenotypes listed…

A: In this case, data from a parental cross and later generations of children are provided to us. If an…

Q: Duchenne muscular dystrophy is an inheritable disorder that results in muscle weakness, leading to…

A: Duchenne Muscular Dystrophy (DMD) is an adult-onset genetic disorder that mainly affects males as it…

Inheritance and Mendelian Genetics

Inheritance means the passing of traits to offspring from parents. These traits could be passed either through asexual reproduction or sexual reproduction. The offspring receives the genetic material from the parents. Mendelian inheritance is a certain biological inheritance that follows the rules and principles laid down by Gregor Mendel in 1865. The initial hypothesis was considered wrong, but other inheritance theories modified the concept of inheritance and thus genetics.