Oculocutaneous Albinism is an inherited autosomal recessive condition caused by a mutation in the tyrosinase (TYR) gene. A male and female who are phenotypically normal, discover through genetic testing that they are both carriers of a TYR mutant allele. What is the probability that their first child will be biologically male and have Oculocutaneous Albinism? Select one: a. 1/8 b. 3/4 c. 1/4 d. 1/16 e. 1/2

Assume that attached earlobes are an autosomal recessive trait with 73% penetrance. If one parent is heterozygous (Aa) and the other homozygous recessive (aa) for the attached earlobe gene, what is the probability that their second child will have attached earlobes? O 73% O 36.5% O 50% O 63.5% O 27% O 13.5% O 18.75%

Duchenne muscular dystrophy is an inheritable disorder that results in muscle weakness, leading to walking and breathing difficulties and heart disease. Which of the following is a valid conclusion about the Duchenne muscular dystrophy pedigree shown above? Select one: a. Only individuals I-2 and II-4 are confirmed carriers of the Duchenne muscular dystrophy allele. b. Individual II-3 can only pass on the Duchenne muscular dystrophy allele to individuals III-2 and III-4. c. Without further evidence, the genotypes of individuals II-2 and III-2 cannot be determined. d. Only individuals I-1 and II-3 are confirmed carriers of the Duchenne muscular dystrophy allele.

Pompe disease is a glycogen storage disorder caused by a lack of ⍺-glucosidase, the enzyme that converts glycogen to glucose in the muscles. Babies born with this disorder die by the age of two. pope disease is a genetic disorder caused by the presence of two recessive autosomal alleles. A. A man and a woman heterozygous for the condition have two female unaffected children. Determine, using a Punnett square, the probability, expressed as a whole number percentage, of a fourth baby being born a male with Pompe disease. B. Iftheman,fromthepreviousquestion,hadtypeAbloodandthewomanhadtypeO blood, what would be probability of them having a daughter with type O blood and affected with Pompe disease? (Show clearly your calculations and express your answer as a frequency between 0 - 1 and rounded to 2 decimal places)