Pompe disease is a glycogen storage disorder caused by a lack of ⍺-glucosidase, the enzyme that converts glycogen to glucose in the muscles. Babies born with this disorder die by the age of two. pope disease is a genetic disorder caused by the presence of two recessive autosomal alleles. A. A man and a woman heterozygous for the condition have two female unaffected children. Determine, using a Punnett square, the probability, expressed as a whole number percentage, of a fourth baby being born a male with Pompe disease. B. Iftheman,fromthepreviousquestion,hadtypeAbloodandthewomanhadtypeO blood, what would be probability of them having a daughter with type O blood and affected with Pompe disease? (Show clearly your calculations and express your answer as a frequency between 0 - 1 and rounded to 2 decimal places)

Human Heredity: Principles and Issues (MindTap Course List)
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Author:Michael Cummings
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Chapter18: Genetics Of Behavior
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Pompe disease is a glycogen storage disorder caused by a lack of ⍺-glucosidase, the enzyme that converts glycogen to glucose in the muscles. Babies born with this disorder die by the age of two. pope disease is a genetic disorder caused by the presence of two recessive autosomal alleles.

A. A man and a woman heterozygous for the condition have two female unaffected children. Determine, using a Punnett square, the probability, expressed as a whole number percentage, of a fourth baby being born a male with Pompe disease.

B. Iftheman,fromthepreviousquestion,hadtypeAbloodandthewomanhadtypeO blood, what would be probability of them having a daughter with type O blood and affected with Pompe disease? (Show clearly your calculations and express your answer as a frequency between 0 - 1 and rounded to 2 decimal places)

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