Name two conditions in which the enzymes involved in the TCA cycle might be inhibited.

Q: What is the mechanism of chymotrypsin catalysed by enzymes without cofactors?

A: CHYMOTRYPSIN is a digestive enzyme of pancreatic juice acting on the duodenum where it performs…

Q: What Is the Chemical Logic of the TCA Cycle?

A: The citric acids cycle is the second stage of cellular respiration where the process of oxidation of…

Q: Why does the enzyme reaction for chymotrypsin proceed in two phases?

A: Enzymes are the biocatalysts that increase the rate of biochemical reactions happening inside the…

Q: Discuss the kreb cycle. How does it work from the start to finish. What is its importance?

A: INTRODUCTION The Krebs cycle, also known as the citric acid cycle or tricarboxylic acid cycle, is…

Q: Which are the two Sources of Cytosolic Ca21+?

A: Cell signaling allows cells to receive and respond to the surrounding signals. This is mediated by…

Q: TPCK and TLCK are irreversible inhibitors of serine proteases. One ofthese inhibits trypsin and the…

A: Both are irreversible inhibitors.

Q: Outline the principal events and outcomes of the Krebs cycle.

A: Krebs cycle is also called as Tricarboxylic cycle or citric acid cycle. The citric acid cycle…

Q: How Is the TCA Cycle Regulated?

A: The citric acid cycle takes place in the matrix of the mitochondrial which was central for cellular…

Q: 1) How is the TCA cycle regulated? a) Draw the TCA diagram that fills in all possible regulation…

A: The citric acid cycle involves the oxidation of acetyl CoA to CO2 and H2O. It is the first common…

Q: Identify ONE similarity and ONE difference between FADH2 and NADPH.

A: Ans: The FADH2 and NADPH are involved in the metabolic process of glucose and other carbohydrate in…

Q: Why is AMP and not ADP the positive regulator of phosphofructokinase?

A: Metabolic pathways are defined as the set of chemical reactions occurring in the body. Metabolic…

Q: Can you please elaborate why blocking the inhibitory G protein from deactivating adenylate cyclase…

A: The inhibitory G protein has a role in the body’s biochemistry, including in the peripheral regions…

Q: Hydroxyurea has been shown to increase the expression of fetal hemoglobin in adult red blood cells,…

A: Sickle cell anemia is the disorder in which abnormality in oxygen carrying hemoglobin present in red…

Q: Describe the two models that explain the binding of allosteric enzymes. Use either model to explain…

A: The allosteric site is a site that allows molecules to either activate or inhibit the enzyme…

Q: The enzyme dihydrofolate reductase (DHFR) normallL can be imported into mitochondria by appending a…

A: This is because methotrexate acts as a competitive inhibitors against the mitochondrial signal…

Q: Describe the reactions catalyzed by nucleoside phosphorylase, adenosinedeaminase, and xanthine…

A: The biosynthesis, interconversion, and degradation of purine/pyrimidine compounds are involved in…

Q: Name three enzymes that are likely the source of bicarbonate ion that is involved with the formation…

A:

Q: State the function and desired products of the hexose monophosphate shunt pathway.

A: Cells metabolize glucose molecules through the glycolytic pathway to release the energy required for…

Q: Glucose-6-phosphatase deficiency (G6PD), also known as von Gierke disease, is glycogen storage…

A: Introduction Carbohydrates, proteins, and fats are the three macronutrients that are present in our…

Q: Tyrosinase enzyme activity is assayed by monitoring the oxidation of 3, 4-dihydroxyphenylalanine…

A: Enzyme activity is defined as the micromole of the substrate formed per minute of reaction. Specific…

Q: Briefly describe the role of nucleophilic catalysis in the mechanism of the chymotrypsin reaction.

A: Chymotrypsin is the enzyme synthesized in the pancreas in the form of the inactive state known as…

Q: What is the major activator (non-allosteric, direct-activator) of phosphorylase?  How does this…

A: The entire number of biochemical processes involved in sustaining the living circumstances of cells…

Q: Explain how genetic mutations of phosphoribosyl pyrophosphate synthetase causing superactivity lead…

A: The overproduction and buildup of uric acid (a waste product of normal chemical processes) in the…

Q: Diisopropylphosphofluoridate (DIPF) inactivates chymotrypsin by covalently modifying serine 195.…

A: Diisopropylphosphofluoridate (DIPF) is an irreversible inhibitor of chymotrypsin. It forms a…

Q: After being stabilized with supplemental oxygen, a blood transfusion, and medication to help with…

A: Hydroxyurea: It is a class of antimetabolites.  This class of drug is used to treat cancer. It is a…

Q: One of your colleagues has obtained a sample of muscle phosphorylase b that is known to be…

A: Glycogen is storage-type homopolysaccharides that contain two types of glucose polymers: amylose:…

Q: Why cant insulin serve as a allosteric activatior for the pyruvate dehydrogenase phospaphate enxyme…

A: The pyruvate dehydrogenase complex is consisting of three enzymes pyruvate dehydrogenase E1,…

Q: Describe type I, II, and III L-asparaginases. Mention characteristics and differences between them…

A: L-Asparaginase Enzymes having antitumor activities. Degrade asparagine to aspartate with the…

Q: Choose the correct answer from the options in brackets. The [positive/negative] standard…

A: Biological oxidation-reduction reactions involve the transfer of electrons from one biomolecule,…

Q: Which of the following dephosphorylates PI 3,4,5-trisphosphate, thereby blocking the activation of…

A: The survival and growth is promoted by the PI3K-Akt signaling pathway. Protein Kinase B and…

Q: Describe the mechanism of the nitrogenase complex in which N2 is converted to NH3.

A: Nitrogen fixation is the process in which N2 is converted into ammonia. This process occurs through…

Q: All the following amino acids produce an intermediate of the TCA cycle except Isoleucine Leucine…

A: TCA cycle or tricarboxylic acid cycle also known as Krebs cycle operates in the mitochondria

Q: draw and label a Michaelis-Menten plot showing the effect of a compentitive inhibitor

A: Two scientists named Leonor Michaelis and Maud Leonora Menten, proposed a model which is known as…

Q: How many GTP molecules are produced in the TCA cycle when you start with a fatty acid molecule that…

A: A fatty acid molecule (18 C) produces more amount of ATP (120) when compared with a glucose…

Q: What is the specific energy currency of the cell produced in the TCA cycle via substrate-level…

A: The citric acid cycle is an intermediate metabolic pathway that involves the oxidation of acetyl CoA…

Q: From the three figures below, indicate which represents best the catalytic pocket of trypsin, a…

A: Serine proteases are the group of enzymes that cleaves the peptide bond in proteins, where Ser…

Q: B-galactosidase Permease A) I POZYA r POZY'A" B-galactosidase Permease B) r POZY'A r PO©ZYA"…

A: Lac operon operates in bacteria so that they may utilize lactose as an energy source when glucose is…

Q: The pathway shown below is used by a fungus to create Fructose-1,6-diphosphate from glucose. A…

A: A mutation is any alteration in the gene sequence of an organism. It may or may not be responsible…

Q: Peroxidase is an enzyme found in many organisms, from plant to humans. The function of peroxidase is…

A: The objective of the first part of the question is to identify two environmental factors that can…

Q: Explain the function of histidine 57 in the mechanism of chymotrypsin.

A: The function of Histidine 57 in the mechanism of chymotrypsin can be described in the following way:…

Metabolic pathways

Metabolism is defined as the group of life-supporting, enzyme-mediated chemical reactions in organisms. A metabolic pathway is a set of these chemical reactions that involve anabolism (synthesis of complex biomolecules) and catabolism (breakdown of biomolecules into small molecules) that occur inside a cell. Metabolites are the reacting substances, products, and intermediate substances of an enzymatic process that are altered by a series of chemical events catalyzed by enzymes.