Describe two types of regulation of the enzyme glutamine synthetase and explain why the regulation of this enzyme is soooo complex.

Q: Why does it make good metabolic sense for phosphoenolpyruvate carbox- ykinase, rather than pyruvate…

A: Phosphoenolpyruvate carboxylase is an enzyme in the family of carboxy-lyases found in plants and…

Q: What are the regulatory means that prevent high levels of activity in glycolysis and gluconeogenesis…

A: Glycolysis is the first step of cellular respiration that deals with the breakdown of glucose to…

Q: describe the mechanism of the phosphoglucoisomerase reaction

A:

Q: What is alpha keto glutarate dehydrogenase complex?. explain very briefly.

A: Tri carboxylic acid (TCA) cycle is an amphibolic pathway that means it involves both catabolic and…

Q: Name the molecules used for gluconeogenesis. What are the sources of these molecules? Under what…

A: Gluconeogenesis is the metabolic process by which organisms produce sugars (namely glucose) for…

Q: rostaglandin-endoperoxide synthase 2, also known as cyclooxygenase- or COX-2, is an enzyme that in…

A: Prostaglandins directly act upon nerve endings to induce pain. They may also speed up the process of…

Q: Describe two different ways in which glucose oxidase is regulated. These mechanisms of regulation do…

A: Glucose oxidase: It is an oxidoreductase that catalyzes the conversion of glucose to hydrogen…

Q: Metformin is a commonly used treatment for type 2 diabetes. The active compound was isolated from…

A: Metformin primarily lowers blood glucose levels by reducing liver glucose production, improving…

Q: Lactate dehydrogenase isoforms contain "H" and "M" subunits. In total, how many subunits are found…

A: - A dehydrogenase is an enzyme that transfers a hydride from one molecule to another. - Enzyme…

Q: Illustrate the detailed mechanism of the transamination reaction in the active site of an…

A: Transamination reaction involves transfers an amino group to a ketoacid to form new amino acids. It…

Q: Complex allosteric regulation of the aspartate transcarbamoylase reaction is significant because it…

A: Aspartate transcarbomylase (ATCase) catalyzes the first step in pyrimidine biosynthesis. Aspartate…

Q: What will happen to the rate of FPP synthesis when FPP concentration is very high Inhibition of an…

A: FPP is farensyl pyrophosphate, one of the intermediates in cholesterol biosynthesis. It is a huge…

Q: A number of genetic deficiencies in acyl CoA dehydrogenases have been described. This deficiency…

A: Medium-chain acyl-coenzyme A dehydrogenase (MCAD) is one of the enzymes involved in mitochondrial…

Q: The enzyme chymotrypsin, catalyses the hydrolysis of nitrophenyl acetate and pther acyl esters. Name…

A: Chymotrypsin is a digestive enzyme belonging to a super family of enzymes called serine proteases.…

Q: Write a balanced equation for the synthesis of PRPP from glucose through the oxidative branch of the…

A: Glucose is catabolized to form pyruvate via glycolysis. Similarly, the pentose phosphate pathway is…

Q: Orotic aciduria results when one of the enzyme activities of UMP synthetase is absent. This syndrome…

A: Orotic aciduria is a hereditary disorder related to metabolism. Orotic aciduria is one of the…

Q: Describe two reasons why the reaction glutamine synthetase performs is important to the body.

A: Cells can accumulate nitrogen in the form of ammonia from amino acid degradation, photorespiration…

Q: Identify the enzyme that controls the oxidative phase of the pentose phosphate pathway.

A: The pentose phosphate pathway is an alternative pathway to glucose oxidation. It is also called…

Q: Describe the γ-glutamyl cycle. How many ATPs are required to synthesize glutathione from oxoproline?

A: γ-Glutamyl Cycle is glutathione salvage pathway, and is an essential pathway for the cell to…

Q: Explain the physiological role of transacetylase ?

A: Transacetylase is an enzyme that transfers an acetyl-CoA to galactosides and lactosides. It is coded…

Q: Identify the three important products of the oxidative pentose phosphate pathway AND indicate how…

A: The Oxidative Pentose Phosphate pathway is a metabolic pathway alternative to glycolysis for…

Q: Propose a mechanism for the conversion of glucose 6-phosphate into fructose 6- phosphate by…

A: Glycolysis is the oxidation process of glucose to yield high-energy compounds such as ATP . The…

Q: The reaction catalyzed by malate dehydrogenase has a ΔG°′ value of +29.7 kJ⋅mol−1. Given what this…

A: Free energy changes in biochemical reactions are denoted by ΔG°', the biochemical standard…

Q: Consider the following Statements: (1) Citric acid cycle intermediates are often the products from…

A: Asked : True statements are to be chosen among the given statements.

Q: the impact of phosphorylation of glycogen phosphorylase on its heterotropic regulation.

A: The impact of phosphorylation of gylcogen phosphorylase on its heterotropic regulation…

Q: What is the major activator (non-allosteric, direct-activator) of phosphorylase?  How does this…

A: The entire number of biochemical processes involved in sustaining the living circumstances of cells…

Q: One    metabolic    scenario that    leads to insulin    resistance is the elevation    of the…

A: Insulin resistance is defined as the inactivity of insulin in its target cells. The examples of…

Q: The clinical signs of two types of galactosemia—galactokinase deficiency or UDPglucose: galactose…

A: Galactosemia is a rare inherited metabolic condition that impairs a person's ability to effectively…

Q: Describe a common feature at the active site of serine proteases and acetyl cholinesterase

A: Acetylcholinesterase is an enzyme that catalyzes the hydrolysis of acetylcholine (which is a…

Q: Why does it make metabolic sense for UTP to inhibit carbamoyl phosphate synthetase II, whereas ATP…

A: Feedback inhibition is a cellular control mechanism in which the activity of the enzyme is inhibited…

Q: Why is the malate–aspartate shuttle system important for gluconeogenesis?

A: Malate aspartate shuttle or malate shuttle performs in the outerside membrane of mitochondria.

Q: Why cant insulin serve as a allosteric activatior for the pyruvate dehydrogenase phospaphate enxyme…

A: The pyruvate dehydrogenase complex is consisting of three enzymes pyruvate dehydrogenase E1,…

Q: During glycogen synthesis, glucose-1P is converted into a molecule called UDPG. This reaction also…

A: The glycogen synthesis takes place in animal tissues. The glycogen synthesis begins with glucose 6-…

Q: If the brain needs glucose, then gluconeogenesis stops after reaction (9, 8, 10, 2) because…

A: Gluconeogenesis is synthesis of glucose from non-carbohydrate precursor molecules such as glycerol,…

Nitrogen metabolism

Nitrogen metabolism is the synthesis, utilization or uptake, breakdown, and excretion of nitrogenous compounds in the body. The nitrogen metabolism encompasses nitrogen fixation, biosynthesis, and the breakdown of amino acids, purines, and pyrimidine. Since nitrogen-containing compounds are required for various life processes, nitrogen is an important element of life.