n the genetically inherited disease called hemophilia. From the information in he pedigree chart (right), answer the following questions: Hemophilia in humans a) If 112 marries a normal man, what is the probability of her first child being a hemophiliac? 1 2 b) Suppose her first child is actually a hemophiliac. What is the chance that her second child will be a boy with hemophilia? 2 3 c) If 114 has children with a hemophiliac man, what is the probability that her first child will be phenotypically normal? d) If the mother of 12 was phenotypically normal, what phenotype was her father?
n the genetically inherited disease called hemophilia. From the information in he pedigree chart (right), answer the following questions: Hemophilia in humans a) If 112 marries a normal man, what is the probability of her first child being a hemophiliac? 1 2 b) Suppose her first child is actually a hemophiliac. What is the chance that her second child will be a boy with hemophilia? 2 3 c) If 114 has children with a hemophiliac man, what is the probability that her first child will be phenotypically normal? d) If the mother of 12 was phenotypically normal, what phenotype was her father?
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:3. The recessive sex-linked gene (h) prolongs the blood-clotting time, resulting
in the genetically inherited disease called hemophilia. From the information in
the pedigree chart (right), answer the following questions:
Hemophilia in humans
(a) If 112 marries a normal man, what is the probability of her first child being
a hemophiliac?
2
(b) Suppose her first child is actually a hemophiliac. What is the chance that
her second child will be a boy with hemophilia?
2
(c) If I14 has children with a hemophiliac man, what is the probability that her first child will be phenotypically normal?
(d) If the mother of 12 was phenotypically normal, what phenotype was her father?
4. The phenotypic expression of a dominant gene in
Ayrshire cattle is a notch in the tips of the ears. In
the pedigree chart on the right, notched animals are
represented by the solid symbols.
Ear notches in Ayrshire cattle
Determine the probability of notched offspring being
produced from the following matings:
1
2
(a) III1 x III3
II
(b) III3 x III2
(c) II13 x II14
(d) III1 x III5
Expert Solution
Step 1
Haemophilia follows X linked recessive pattern. The genes associated with this condition are located on the X chromosome, which is one of the two sex chromosomes. In males (who have only one X chromosome), one altered copy of the gene in each cell is sufficient to cause the condition
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