Shown below is a pedigree for Phenylketonuria (PKU), an autosomal recessive metabolic disorder. The characteristic feature of PKU is severe mental retardation A) What is the probability that individual II-1 is heterozygous for this gene? B) What is the probability that individual III-4 is heterozygous for this gene? C) If individuals III-3 and III-4 were to marry, what is the probability that their child would express PKU?
Shown below is a pedigree for Phenylketonuria (PKU), an autosomal recessive
A) What is the probability that individual II-1 is heterozygous for this gene?
B) What is the probability that individual III-4 is heterozygous for this gene?
C) If individuals III-3 and III-4 were to marry, what is the probability that their child would express PKU?
Phenylketonuria (PKU) is an autosomal recessive disorder.
Autosomal recessive trait characteristics:
Two copies of the recessive allele must be present to Express in the phenotype. It is passed down to both males as well as females from the parents. It is not sex linked , means it is not related to single sex.
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