Match each inhibitor with its effect on Michaelis-Menten reactions.   Group of answer choices Vmax and apparent Vmax are equal and the apparent Km is greater than Km.                                                                              The apparent Vmax is less than Vmax and the apparent Km and Km are equal                                                                              The apparent Vmax and the apparent Km are both lowered to the same

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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Match each inhibitor with its effect on Michaelis-Menten reactions.

 

Group of answer choices
Vmax and apparent Vmax are equal and the apparent Km is greater than Km.
 
                                                                        
 
The apparent Vmax is less than Vmax and the apparent Km and Km are equal
 
                                                                        
 
The apparent Vmax and the apparent Km are both lowered to the same degree.
 
                                                                        
 
The apparent Vmax is less than Vmax and the apparent Km can be either greater than or less than Km.
 
                                                                        
Expert Solution
Michealis Menten kinetics

Michealis menten kinetics can be described by using the following equation:

Biochemistry homework question answer, step 1, image 1

Where V is velocity of the reaction 

Vmax is the maximum velocity 

[S] is the substrate concentration 

Km is the Michealis Menten constant or the substrate concentration at which half of the maximum velocity is reached.

The same equation can be rearranged into Equation shown below called as Lineweaker Burk equation: 

Biochemistry homework question answer, step 1, image 2

A plot of 1/V vs 1/[S] gives a straight line.

In the next section we see how inhibitor effects the Km and Vmax of a reaction.

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