inheritance patterns in traits, especially continuous ones, cannot be accounted for by Mendelian genetics. Why might this be? Select all that apply.
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Many inheritance patterns in traits, especially continuous ones, cannot be accounted for by Mendelian genetics. Why might this be? Select all that apply.
-
A.
The trait might not be controlled by any genes.
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B.
The trait might have multiple genes that control it.
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C.
There might not be any alleles that result in the trait.
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D.
There might be more than two alleles that result in the trait.
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E.
Two alleles might be codominant for the trait.
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F.
The trait might not have any codominant alleles.
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- Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you decide to have a child if the test results said that you carry the mutation for breast and ovarian cancer? The heart disease mutation? The TSD mutation? The heart disease and the mutant alleles?Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. Would you want to know the results of the cancer, heart disease, and TSD tests if you were Sarah and Adam? Is it their responsibility as potential parents to gather this type of information before they decide to have a child?Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a Mendelian pattern of inheritance. It can also be used to help identify individuals within a family who may be at risk for the trait. Adam and Sarah, a young couple of Eastern European Jewish ancestry, went to a genetic counselor because they were planning a family and wanted to know what their chances were for having a child with a genetic condition. The genetic counselor took a detailed family history from both of them and discovered several traits in their respective families. Sarahs maternal family history is suggestive of an autosomal dominant pattern of cancer predisposition to breast and ovarian cancer because of the young ages at which her mother and grandmother were diagnosed with their cancers. If a mutant allele that predisposed to breast and ovarian cancer was inherited in Sarahs family, she, her sister, and any of her own future children could be at risk for inheriting this mutation. The counselor told her that genetic testing is available that may help determine if this mutant allele is present in her family members. Adams paternal family history has a very strong pattern of early onset heart disease. An autosomal dominant condition known as familial hypercholesterolemia may be responsible for the large number of deaths from heart disease. As with hereditary breast and ovarian cancer, genetic testing is available to see if Adam carries the mutant allele. Testing will give the couple more information about the chances that their children could inherit this mutation. Adam had a first cousin who died from Tay-Sachs disease (TSD), a fatal autosomal recessive condition most commonly found in people of Eastern European Jewish descent. Because TSD is a recessively inherited disorder, both of his cousins parents must have been heterozygous carriers of the mutant allele. If that is the case, Adams father could be a carrier as well. If Adams father carries the mutant TSD allele, it is possible that Adam inherited this mutation. Because Sarah is also of Eastern European Jewish ancestry, she could also be a carrier of the gene, even though no one in her family has been affected with TSD. If Adam and Sarah are both carriers, each of their children would have a 25% chance of being afflicted with TSD. A simple blood test performed on both Sarah and Adam could determine whether they are carriers of this mutation. If Sarah carries the mutant cancer allele and Adam carries the mutant heart disease allele, what is the chance that they would have a child who is free of both diseases? Are these good odds?
- Which of the following is false? a. the pollen grain shape was studied by Mendel. b. Mendel believed that the characteristics of pea plants were determined by the inheritance units or factors from both parents. c. An allele is one of several possible forms of a gene. d. When the genotype consists of a dominant and recessive allele, the phenotype will be like the dominant allele.Which of the following statements describes the multifactual inheritance in genetics? A. One locus is associated with different traits. B. One locus is associated with variable phenotypes of a trait. C. Several loci are associated with the trait.In humans, having extra fingers or toes is caused by a dominant allele (E). People with two recessive alleles have 5 fingers and toes on each hand or foot. a. What is the genotype of someone who has 5 fingers and toes on each hand or foot?b. What are the two different genotypes that someone with extra fingers or toes could have?c. If two people both had the normal number of fingers and toes, is there any chance that their children could inherit the allele for extra fingers and toes? Do a Punnett square and show your work.d. If a man who was heterozygous for this gene married someone who was homozygous for the recessive allele, what fraction of their children would you expect to have extra fingers or toes? Do a Punnett square and show your work.
- Fruit flies are very useful model organisms that have been used to study genetics. One mutant recessive trait in fruit flies is called "eyeless" because it causes flies to have no eyes. Cross an eyeless fly with a homozygous normal fly. a. Draw the Punnett square. b. What is the genotyoe ratio of the offspring? c. What is the phenotype ratio of the offspring? d. What genetic problem is this? (monohybrid, dihybrid or multiple allele)The chart below is showing 4 generations of a family that is affected by a hereditary disease. a. Is the disorder being tracked dominant or recessive? How do you know? b. There is only one possible genotype for person C. True or False? c. What are the possible genotypes for person A? d. What are the possible genotypes for person B?, e. If two people with the same genotypes as person C's spouse and person A's spouse had a child, what is the probability that the child will be affected by this genetic disorder? (draw a Punnett square using the correct genotypes to help you). % chance offspring will be affected % chance offspring will not be affectedWhich of the following is false, regarding the law of segregation? A. It states that each of two alleles for a given trait segregate into different gametes. B. It can be explained by the segregation of sister chromatids during mitosis. C. It can account for the 3:1 ratio seen in the F2 generation of Mendel's crosses. D. It can be used to predict the likelihood of transmission of certain genetic diseases within families.
- Which if the following is not among Mendels principles? a. There are factors that is transmitted from parent to offspring? b. There are only two kinds of traits, dominant and recessive c. Genes resides in the chromosome d. Pair of single traits segregate randomlyWhat was the most significant conclusion that Gregor Mendel drew from his experiments with pea plants? Select one: a. There is considerable genetic variation in garden peas. b. Genes are composed of DNA. c. Recessive genes occur more frequently in the F1 generation than do dominant ones. d. Traits are inherited in discrete units (genes), and are not the results of "blending."Albinism is a recessive trait in humans. A geneticist studies families in which both parents are normal and at least one child has albinism. The geneticist reasons that both parents in these families must be heterozygous and the albinism should appear in 1⁄4 of the children of these families. To his surprise, the geneticist finds the frequency of albinism trait is quite high. As a consultant, can you suggest an explanation for the higher expected frequency of albinisms in these families?