In individuals with hereditary alkalosis, common symptoms include the accumulation of HCO) (bicarbonate) and an increase in the pH value of the blood plasma. This condition is associated with mutations in the genes that control anion exchange proteins, specifically the chloride-bicarbonate exchanger Band 3. Explain how the anion exchange proteins work in the capillaries of normal people's body tissue and discuss how this process might be disrupted in alkalosis patients and lead to these symptoms.

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter11: The Blood
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In individuals with hereditary alkalosis, common symptoms include the accumulation of
HCO3 (bicarbonate) and an increase in the pH value of the blood plasma. This condition
is associated with mutations in the genes that control anion exchange proteins,
specifically the chloride-bicarbonate exchanger Band 3.
Explain how the anion exchange proteins work in the capillaries of normal people's body
tissue and discuss how this process might be disrupted in alkalosis patients and lead to
these symptoms.
Transcribed Image Text:In individuals with hereditary alkalosis, common symptoms include the accumulation of HCO3 (bicarbonate) and an increase in the pH value of the blood plasma. This condition is associated with mutations in the genes that control anion exchange proteins, specifically the chloride-bicarbonate exchanger Band 3. Explain how the anion exchange proteins work in the capillaries of normal people's body tissue and discuss how this process might be disrupted in alkalosis patients and lead to these symptoms.
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