Explain why it is necessary to wash and save erythrocytes in a 290 mUsm /L saline solution rather than in pure water.

With toxic damage to the liver cells, with a violation of its functions, the patient developed edema. What changes in the composition of blood plasma are the leading cause of the development of edema? Justify the answer.

The inorganic compound most abundant on plasma cell is

▪ An important PK relationship at steady state is Cavg,ss=(FXD/tau)/Cl. This means that if a patient's clearance drops, the concentration will A) increase B) decrease

What would happen if RBCs were placed in a 0.9% NaCl (physiological salinesolution)? Will osmosis occur? If so, what direction would water move?

In what conditions does the MCV vary?

A 37-year-old man whose respirations are being maintained by a mechanical ventilator has the following arterial blood volume: i. pH 7.50ii. PCO2 20 mm Hg iii. HCO3- 15 mEq/L Which of the following is also expected in this patient? a) Decreased intracellular pH b) Increased serum concentration of ionized calcium c) Increased serum concentration of potassium d) Increased urinary concentration of ammonium e) Increased urine pH

EXPLAIN WHY? A drug is has half life of 7 h and volume of distribution 20 Lwas given by contant infusion at a rate of 40 mg/h.Assuming one compartment model, the steady stateconcentration is……?A) 10.2 mg/mLB) 20.2 mg/LC) 20.2 mg/mLD) 15.5 mg/mLE) 15.5 mg/L A drug with half live of 10 h and Vd 15 L was given byconstant infusion to achieve required steady stateconcentration of 0.5 mcg/ml.• How much time it requires to achieve 95% of desiredCss?

Explain why erythrocytes are unique in shape and structure. Describe all the factors that make them ideal for transporting oxygen to cells.

Infuse a unit of whole blood (300 ml/unit) to infuse in 2 hours. Drop factor 20 gtts/ml.