Retinitis pigmentosa, a form of blindness in man, maybe caused either by a dominant autosomal gene R, or a recessive autosomal gene a. An afflicted man whose parents are both normal marries a woman with genotype AaRr. a. What proportion of the children are expected to suffer from this affliction if R and A are inherited independently? b. If this couple want to have normal children only, what is the probability of having normal children?

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TO င် ၅ဝပ် တွင် တွင် ၏ ဝ DO (A) The blue trait is inherited as an autosomal recessive trait which means that affected individuals have copies of a mutant gene. (B) Indicate which individuals are carriers of the "blue" gene by placing the letters Bb next to their symbol. (C) What is the relationship of the parents of the "blue" children? (D) What is the probability that the unaffected siblings of the "blue" children are carriers for the "blue" trait? (E) What warning does marrying close relatives does this illustrate?

36. Look at this pedigree and circle each row yes/no. Any assumption (that is not outrageous) can be made), for example, can assume someone is a carrier. a. Could this trait be inherited as a simple autosomal recessive? YES oo 8995 ON b. Could this trait be inherited as a simple autosomal dominant? YES ON C. Could this trait be inherited as a simple x linked recessive? YES ON d. Could this trait be inherited as a simple x linked dominant? YES ON e. Could this trait be inherited as a Y linked? YES ON