If the initial allele frequencies are p = 0.5 and q = 0.5 and allele a is a lethal recessive, what will be the frequencies after one generation?

In the genetics unit you learned that sickle cell anemia is an autosomal recessive condition.  In 2016, assume in the City of Markham there are 1000 people out of 300000 people who have sickle cell anemia.  Assume global warming continues for the next 50 years and in the year 2066 there are 20000 people out of 500000 in Markham who have sickle cell anemia.                                                                                                        a)What are the allele frequencies in 2016?  What are the allele frequencies in 2066? Is microevolution evident?                                                                                                                                                       b)Due to global warming, assume the numbers of malaria carrying mosquitoes in Markham dramatically increased between 2016 and 2066.  What do you believe is the main cause of the microevolution in Markham?  (Hint- refer to the 5 factors affecting microevolution and refer back…

If the frequency of the dominant allele is 0.4, what is the frequency of the recessive allele?

In a population of Hopi indians the autosomal recessive gene for albinism exists at an allele frequency of 0.04. What proportion of these individuals are expected to be heterozygous?

If the frequency of those exhibiting a monogenic autosomal recessive phenotype caused by only one known clinically relevant allele is 1/8500 in a given population, what is the frequency of the wild type allele? Please give your answer as a percentage to 3 decimal places, do not include the % symbol.

Cystic fibrosis is an autosomal recessive disease characterized by two copies of a mutated CFTR gene.  If one in 100 (hypothetical scenario, not reality) people in the United States have cystic fibrosis, calculate the p and q frequency for the normal allele (p) and the mutated allele (q). Based on those calculations, what percentage of individuals would be expected to be homozygous dominant?

If the frequency of those exhibiting a monogenic autosomal recessive phenotype caused by a rare clinically relevant allele is 1/8500 in a given population, what is the carrier frequency? Please give your answer as a percentage to 3 decimal places, do not include the % symbol.   ANSWER: In a population where the frequency of those exhibiting a monogenic autosomal recessive phenotype caused by only one known mutation is 1/8500 the carrier frequency is a percent.

What percent of offspring will be homozygous recessive if the genotypic ratio is 4:0:0.  (For your answer write the number and the percent sign, example:  32%)

An autosomal locus has alleles A and a. We are given the frequency of individuals with the autosomal recessive phenotype. Which of the following statements is TRUE?  Choose all that are true. Note: HWE = Hardy-Weinberg equilibrium a) If we assume HWE, we can calculate both allele frequencies b) If we assume HWE, we can calculate the genotype frequencies that we weren't given c) We can calculate both allele frequencies even if we don't assume HWE d) We can calculate q = Freq(a) even if we don't assume HWE e) Even if we don't assume HWE, we can calculate the genotype frequencies that we weren't given

In a population of 200 people, an allele F has a frequency of 84%. What is the frequency of allele f? Using the Hardy-Weinberg equation, estimate the numbers of homozygous dominant, heterozygous, and homozygous recessive genotypes. (Remember that the formula is: p2 + 2pq + q2 = 1, where p represents the dominant allele and q represents the recessive allele.) *Be sure to account for all 200 people in the population.