if each NADH generates 3 ATP molecules and each FADH2 generates 2 ATP molecules, calculate the number of ATP molecules generated from one saturated 10-carbon fatty acid Determine the number of repetitions of the β‑oxidation spiral needed to completely degrade the fatty acid to acetyl-SCoAacetyl-SCoA (acetyl-CoA)(acetyl-CoA) . Calculate the ATPATP produced by the acetyl-SCoAacetyl-SCoA molecules in the citric acid cycle. Calculate the ATPATP produced from the FADH2FADH2 and NADHNADH produced from β‑oxidation. Add the ATPATP generated (from step 2 and 3), and subtract the ATPATP needed to activate the fatty acid.

if each NADH generates 3 ATP molecules and each FADH2 generates 2 ATP molecules, calculate the number of ATP molecules generated from one saturated 10-carbon fatty acid Determine the number of repetitions of the β‑oxidation spiral needed to completely degrade the fatty acid to acetyl-SCoAacetyl-SCoA (acetyl-CoA)(acetyl-CoA) . Calculate the ATPATP produced by the acetyl-SCoAacetyl-SCoA molecules in the citric acid cycle. Calculate the ATPATP produced from the FADH2FADH2 and NADHNADH produced from β‑oxidation. Add the ATPATP generated (from step 2 and 3), and subtract the ATPATP needed to activate the fatty acid.

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter27: Metabolic Integration And Organ Specialization

Section: Chapter Questions

Problem 8P: Ethanol as a Source of Metabolic Energy (Integrates with Chapters 19 and 20.) Acetate produced in...

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Ethanol as a Source of Metabolic Energy (Integrates with Chapters 19 and 20.) Acetate produced in ethanol metabolism can be transformed into acetyl-COA by the acetyl thiokinase reaction: Acetate+ATP+CoASHacetyleCoA+AMP+PPiAcetyle-CoA then can enter the citric acid cycle and undergo oxidation to 2 CO2by this route, assuming oxidative phosphorylation is part of the process? (Assume all reactions prior to acetyl-CoA entering the citric acid cycle occur outside the mitochondrion). Per carbon atom, which is a better metabolic fuel, ethanol or glucose? That is, how many ATP equivalents per carbon atom are generated by combustion of glucose versus ethanol to CO2?
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Calculate the number of ATPS generated from the metabolic oxi- dation of the four carbons of acetoacetyl-CoA to CO,. Now consider the homolog derived from oxidation of an odd-numbered carbon chain, namely propionoacetyl-CoA. Calculate the net ATP yield from oxidation of the five carbons of this compound to CO,.
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Consider the complete oxidation of one mole of simple TAG containing lignoceric acid residues (24:0). 1. For one mole of the fatty acid residue, determine the following: a. ATP yield obtained from the oxidation of acetyl CoA entering the TCA cycle and ETC I b. ATP yield obtained from NADH coming from the complete ß-oxidation of the fatty acid residue c. ATP yield obtained from FADH₂ coming from the complete ß-oxidation of the fatty acid residue d. net ATP yield of ATP in the complete oxidation of the fatty acid residue 2. What is the net ATP yield for the complete oxidation of all the fatty acid residues of the simple TAG? (Note: glycerol backbone is not included) REMINDER: Answer the following items using numerical value only (e.g. 1, not "1 ATP")
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