How are the genes in the beta-globin locus different from each other? They have different evolutionary origins, from different ancestral genes. B) They have different sequences and locations on the chromosome. They are expressed at different times in development. (D) Some are expressed in all cells; some are expressed only in red blood cells. (E) They are dispersed on on different chromosomes.

Q: Suppose a gain-of-function mutation happens in an oncogene. Which of the following changes is likely…

A: Cancer causing gene is known as oncogenes and its an abnormal active gene which promotes growth of…

Q: If you were to design an experiment to get p53 back into cancer cells, how would you go about that…

A: p53 Is a nuclear transcription factor that promotes apoptosis. Because over 50% of human cancers…

Q: My Avya mouse is brownish because a) the CpG island with the transposon is unmethylated. b) it was…

A: Epigenetic systems that facilitate gene-environment interactions are involved in the ability of…

Q: In a few sentences, describe how p53 guards the genome. Include at least two specific ways that p53…

A: The TP53 ( Tumor protein 53) also known as P53. This gene codes for cell cycle regulatory proteins…

Q: A mutation occurs in a gene, resulting in it being expressed at the wrong time during development.…

A: The mutation refers to change the sequence of nucleotide in a gene.

Q: Match each one (they can be repeated): 1) Plasminogen- Plasmin 2) Pro-insulin- Insulin 3) CFTR…

A: Transcription and translation are two crucial mechanisms of all living cells. The enzyme  RNA…

Q: A friend of yours who works at a biotechnology start up company has computationally designed three…

A: The application of scientific and technical principles to the processing of the material by…

Q: Which of the following is true about the HesC gene? Choose all possible answe a) repressed by the…

A: Hematopoietic Stem Cells (HSCs) are the main cells inside the hematopoietic system that have the…

Q: Centers of transcriptional repression that are usually associated with lamina or found around…

A: Barr bodies are transcriptionally repressed centers meaning that most genes on the inactivated X…

Q: Insulin is a peptide hormone encoded by the INS gene, which is on chromosome 11. Insulin is produced…

A: The hormone insulin is required by the body to reduce the level of blood glucose. The pancreatic…

Q: Genetic tests that detect mutations in the BRCA1 and BRCA2 oncogenes are widely available. These…

A: Young woman in a suspected breast cancer family takes the BRCA1 and BRCA2 genetic tests and receives…

Q: A hypothetical cell lineage is shown here. A gene, which we will call gene X, is activated in the…

A: The term heterochronic indicates the cellular and tissue level development that takes place at an…

Q: The following interactions occur during the expression and secretion of an antibody heavy-chain…

A: 1. A signal peptide sequence and a signal recognition particle (SRP) interact (Step c):  - Early in…

Q: Regulation of gene expression is necessary because: A) all cells do not need to express all genes…

A: Gene expression is the process by which the instructions in our DNA are converted into a functional…

Q: Most human viruses associated with cancers activate:  a.) nuclear factor-kB (NF-kb) b.) apoptosis…

A: Cancer is a pathological condition characterized by uncontrolled cell division, proliferation and…

Q: The phenotype of a heterozygous mouse (Aa) is agouti.  The agouti banding pattern is due to altered…

A: * Homozygous dominant and Heterozygous will produce agouti that is AA or Aa respectively  and the…

Q: Rho independent terminators Select an answer and submit. For keyboard navigation, use the up/down…

A: Transcription is the process in which the RNA is formed out of the DNA. The process of transcription…

Q: B-thalassemia is a hereditary blood disorder that leads to the formation of an abnormal hemoglobin…

A: Answer is  option A.

Q: The decision by some high-risk women to have their breasts removed to prevent the possibility of…

A: The type of gene that possesses the potential to cause cancer as a result of mutation is referred to…

Q: Alpha-1 antitrypsin has codominant inheritance. M genes express normal levels. S and Z genes have…

A: Emphysema is caused by deficiency in Alpha 1 antitrypsin.This disorder causes lung diseases and…

Q: [GAINI- is a protein coding gene that regulates cardiomyocyte metabolism in patients with heart…

A: Cardiovascular refers to the circulatory system. The circulatory system, which includes the heart…

Q: Researchers sought to grow blood vessels in a lab for implantation into patients with clogged…

A: Introduction :- Coronary arteries are blood vessels that supply oxygenated blood to the heart…

Q: You have a precursor protein that is translated in the cytosol with an N-terminal mitochondrial…

A: The mitochondria is a double membrane bound cell organelle that is responsible for energy (ATP)…

Q: How do loss of function mutations associated with Artemis (protein) cause their resulting…

A: Introduction: -Artemis is a protein that in humans is encoded by the DCLRE1c gene.  Function: -…

Q: Some people with neurofibromatosis develop blemishes on their skin, while others are severely…

A: Neurofibromatosis is a genetic disorder that causes tumors to form on nerve tissue. These tumors can…

Q: Which of the following statements about cancer is false? (a) oncogenes arise from mutations in…

A: Proto Oncogenes are the genes that cause cancer when there are alterations in them. Several factors…

Q: Wnt4 is expressed in a variety of embryonic tissues. You decide to study this gene during mouse…

A: Wnt4 gene -- Wtn4 name is derived from the first two family members discovered in int1 mouse and…

Q: A mutation takes place that switches a codon from ACG to ACA. What type of mutation is this? A)…

A: A mutation is a random change in the DNA sequence.

Q: Choose all of the following that you think are correct Protein(s) that play a role in initiating…

A:

Q: Researchers use a technique call RNA interference to knock down (i.e. not completely gone) the Bcl-2…

A: RNA is the nucleic acids similar to the DNA and contains uracil instead of the thymine. It plays…

Q: SCENARIO: MM, a 54-year old female presents to the Family Medicine Clinic due to a 2-week history…

A: Glyburide is used for treating diabetes mellitus type II by the mechanism of increasing the insulin…

Q: When  regulatory protein binds to a mature mRNA in the cytoplasm and prevents it from binding to a…

A: Translational regulation is the mechanism that aims to control the levels of protein synthesis from…

Q: A temperature-sensitive mutant allele of Ras causes the Ras protein to be fixed in the GDP-bound…

A: Introduction The various kinds of genes that have an abnormal function at higher temperatures and…

Q: Why do Tbx5 mutations affect limbs and heart but no other tissues?

A: Introduction Mutation can be defined as the change in the DNA sequence or a structural change in the…

Q: a) b) c) d) Spongebob's dream is to become like Larry the lobster, a strong, handsome bodybuilder.…

A: Receptors are the proteinaceous substances that are responsible for binding of the ligands. These…

Q: Based on the data provided, explain how cellular processes must be altered in stomach cancer cells…

A: In comparison to healthy cells, cancer cells have an active metabolism and need more energy. Cancer…

Q: A greater number of protocadherin genes ____.

A: Protocadherins are a family of cell adhesion molecules, and they play a crucial role in neuronal…

Q: Cancer-causing mutations in genes can have different effects on the protein products expressed.

A: An Oncogene is a gene that encodes a protein that has the potential to transform cells in culture or…

Q: Many oncogenes result from mutations that cause excessive expression of a protein in cells where it…

A: The questions asks to find the correct option for the given statement“Most of the oncogenes arise…

Q: SCENARIO: MM, a 54-year old female presents to the Family Medicine Clinic due to a 2-week history…

A: Introduction:-  Breast carcinoma is very common cancer in females and occurs most commonly in the…

Q: Which of the following statements correctly describes p53? Which of the following statements…

A: Answers are option B and E.

Q: General transcription factors Select an answer and submit. For keyboard navigation, use the up/down…

A: The general transcription factors bind to other proteins or to a sequence element within the…

Q: In 2013 the actress Angelina Jolie elected to have prophylactic double-mastectomy surgery to prevent…

A: Cancer is an uncontrolled division of cell that has a defunct apoptosis mechanism. Usually, when…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.