Given a mutation in the promoter, coding region, and/or non-coding region of a gene, explain how these three scenarios create new alleles of the same gene.

Q: Genes with highly similar sequence are often located adjacent one another in the genome. Gene…

A: Linked genes are genes that are tightly placed on the same chromosome and tend to inherit together.…

Q: If the gene product is protein then why not to provide these protein from exogenous source to meet…

A: DNA undergoes transcription to form RNA which then undergoes translation to form DNA.

Q: Please answer  A mutation within an enhancer sequence regulating the expression of the ABC1 gene…

A: The transcription is the process by the RNA is produced from the DNA and this is the first step of…

Q: A person treated successfully by gene therapy will still have a defective copy of the gene. Explain…

A: Genes are the basic unit of heredity. The study of heredity is called Genetics. The father of…

Q: Briefly discuss why mutant allele 1 fails to produce functional protein. Note that this mutation has…

A: A gene is a DNA-based functional heredity unit that delivers instructions for the production of RNA…

Q: Explain what happens to the sequence of DNA during trinucleotiderepeat expansion (TNRE). If someone…

A: TNREs are a special kind of mutation, where in a sequence of three nucleotides are repeated (tandem…

Q: Give at least 3 examples each of internal and external factors that affect penetrance and…

A: Penetrance is a term used to define whether or not a genotype has a clinical expression in a person.…

Q: Which step of the Central Dogma is responsible for transmission of genetic information from…

A: The central dogma is a process through which the information present in the DNA is converted into…

Q: In references to the "alpha-globin gene locus" or "beta-globin gene locus", the term "locus" means

A: Chromosomes are condensed form of chromatin. Chromosomes consist of two chromatids which are held…

Q: A principle of biology is the genetic material provides ablueprint for reproduction. Explain how…

A: The DNA (deoxyribonucleic acid) is the hereditary unit of an organism. It consists of purines and…

Q: Missense and nonsense mutations can occur in both the protein coding region and the regulatory DNA…

A: Is Missense and nonsense mutation occur in both protein coding region and the regulatory DNA of a…

Q: Select all the possible mutation types for the following observed phenotype resulting from a…

A: Need to find which of the following mutation is happened in protein to express in wrong cell

Q: Northern blot is an analytical technique commonly performed to study gene expression in experimental…

A: A tissue is defined as a group of cells that possess a similar structure and perform a specific…

Q: How would you explain gene expression? How is it that a particular genotype is actually expressed as…

A: The central dogma is the flow of information that is carried by a gene that is expressed in the form…

Q: Many genes generate different products depending on the type of cell expressing the gene. How is…

A: The process of generation of different protein products from the same pre-mRNA transcript is called…

Q: Explain the difference between a gain-of-functionmutation and a dominant-negative mutation. Why…

A: A mutation is referred to as a change in an organism's DNA sequence. Mutations can occur as a result…

Q: All the cells of one organism share the same genome. However, during development, some cells develop…

A: Developmental biology and stem cell biology helps us to understand more about the fate of cells. The…

Q: Explain how a loss-of-function allele in a gene encoding a cohesin protein could be dominant to…

A: Cornelia de Lange syndrome (CdLS) is a rare human disease caused by a dominant loss-of-function…

Q: A person treated successfully by gene therapy will still have a defective copy of the gene. Explain…

A: A gene is the fundamental structural and functional unit of heredity. Genes are comprised of DNA…

Q: One mutation is a deletion of six nucleotides in the second exon of the gene and the other mutation…

A: Introns and exons are nucleotide sequences within a gene in mRNA. The conversion of DNA to RNA is…

Q: Why is it useful to survey expression of the entire genomeunder particular conditions?

A: Expression of the entire genome involves studying expression and the variation in expression in a…

Q: When the organization of adjacent genes with highly similar sequences is in an inverted orientation,…

A: The physical unit of heredity is known as the gene. The term "inversion" refers to a mutation that…

Q: three different types of loss of function mutations and in each case explain how the mutation exerts…

A: A mutation is any alteration of the base sequence of the DNA or RNA. Since mutation alters the base…

Q: Describe the difference in the effects of a mutation in a gap gene versus one in a pair-rule gene.

A: The genes consist of hereditary information in the deoxyribonucleic acid (DNA) sequences and is…

Q: A gene, which we will call gene C, can be epigenetically modified in such a way that its expression…

A: Introduction: Gene is the structural and functional unit of inheritance or heredity which transfers…

Q: The HbβS(sickle-cell) allele of the human β-globingene changes the sixth amino acid in the…

A: Sickle cell anemia is a blood disorder in which an improper folding of hemoglobin occurs. In this…

Q: Based on Figure 17-35, write a sentence stating howtranslocation can lead to cancer. Can you think…

A: Translocations were discovered cytologically for the first time in the late nineteenth and early…

Q: The number of protein-encoding genes in a prokaryotic cell equals the number of proteins that can be…

A: Genes encode proteins and dictate cellular functions. The genes expressed in a particular cell…

Q: Explain why loss-of-function hedgehog and smoothened mutations yield the same phenotype in flies,…

A: The Hedgehog signalling pathway is responsible for transferring information to embryonic cells.…

Q: explain the statement Transposons can move genes to newchromosomal locations.

A: Transposons are referred to as chromosomal segments which can undergo transposition.

Q: Briefly explain how or why making a region of DNA heterochromatic results in little or no expression…

A: DNA consists of two regions euchromatin and heterochromatin. heterochromatin are darkly stained…

Q: Cystic fibrosis (CF) is a genetic disorder affecting a number of organs, including the lung airways,…

A: many types of mutations are present which can explain the cause of the data we see above as cystic…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.