Define copy number variants (CNVs)

Q: Is lambda DNA circular or linear?

A: Lambda DNA is derived from an E.coli bacteriophage.

Q: Two homologous chromosomes in ES cells are depicted below with the portion of your gene of interest…

A: CRISPR/Cas9 creates specific double-stranded breaks at the target locus that trigger DNA repair…

Q: Define origin-recognition complex (ORC)

A: The field of biology that studies the composition, and structure of the molecules and also the…

Q: Compare and contrast transposons and genomic islands.

A: The transposons move from one genomic location to the another genomic location by the cut and paste…

Q: explain Scope of heterochromatin effects?

A: Chromatin means DNA +proteins (histones) or histones combine with DNA known as chromatin. Both the…

Q: Define recombinant protein.

A: Recombinant DNA is also known as rDNA molecules. It is an artificially prepared DNA strand which is…

Q: Define the Dna methylation.

A: DNA is copied by the process of DNA replication, which uses existing DNA strands to create new DNA…

Q: 1. a)What would happen if the aminoacyl tRNA synthetase responsible for charging alanine tRNAs also…

A: The polymerization of amino acids according to the codons on mRNA to form proteins is known as…

Q: Explain Exon shuffling via recombination between homologous interspersed repeats.

A: Answer: Introduction: Exon shuffling is a process of the production of new genes. It is a mechanism…

Q: Explain why all transposons include inverted repeats.

A: Transposable elements (TEs) are deoxyribonucleic acid (DNA) sequences that move from one location to…

Q: Describe the molecular steps by which polycomb groups cause epigenetic gene silencing.

A: Polycomb group (PcG) proteins are members of the protein family that were initially discovered in…

Q: Describe how DNA methylation is heritable.

A: DNA (deoxyribonucleic acid) methylation involves the addition of methyl groups to cytosine bases…

Q: Explain Exon shuffling by transposition.

A: Exon shuffling is a molecular mechanism for the formation of new genes. There are different…

Q: Discuss the effects of transposable elements on gene function.

A: Transposable elements also known as jumping genes these are short sequences of DNA that have the…

Q: Given a mutation in the promoter, coding region, and/or non-coding region of a gene, explain how…

A: The mutation is a sudden heritable change in the genetic makeup of a cell which mostly results in…

Q: Explain the reason that CG dinucleotides are underrepresented in the human genome than E.coli.

A: Due to metabolic mistakes, radiation exposure, and environmental variables, DNA experiences numerous…

Q: How do we know if a genomic DNA sequence contains aprotein-coding gene?

A: Only about 1% of DNA contains protein-coding genes; the remaining 99 percent is noncoding. Noncoding…

Q: Why is it useful to survey expression of the entire genomeunder particular conditions?

A: Expression of the entire genome involves studying expression and the variation in expression in a…

Q: Define the term Transposons and show the shifting segments of the genome.

A: Barbara McClintock in New York discovered transposable elements more than 50 years ago. Initially,…

Q: Discuss the mechanism of DNA recombination and its role in a variety of biological processes.

A: DNA recombination is a process by which new combinations of DNA or alleles are obtained by breaking…

Q: like this

A: Aldehyde dehydrogenases are enzymes that convert aldehydes to acids. They play a role in the…

Q: Based on Figure 17-35, write a sentence stating howtranslocation can lead to cancer. Can you think…

A: Translocations were discovered cytologically for the first time in the late nineteenth and early…

Q: There is a situation in which a gene has five exons. Please draw four possible mature products of…

A: Alternative splicing is a biological process that involves the joining of exons from the same gene…

Q: Define transposable element

A: Transposable elements are present in the DNA of an organism that can cause mutations and alter the…

Q: Define repetitive sequence and explain how this type ofsequence affects genome sizes

A: DNA molecules are made up of polynucleotide chains. These chains are coiled around each other and…

Q: Explain how exon shuffling can be due to unequal homologous recombination.

A: Exon shuffling is defined as a molecular process for the arrangement of new genes. It is a cycle…

Q: Briefly explain why CpG islands might have come to be underrepresented in eukaryotic genomes.

A: CpG islands are the sites of methylation on DNA. Methylation of DNA occurs to silence some genes of…

Q: Describe the function of telomere repeat-binding factors.

A: Telomeres are the ends of chromosomes. they are made up of short repetitive sequences and prevent…

Q: Describe what a pseudogene is and what impact they have on gene expression

A: A pseudogene is a nonfunctional gene that can be compared to junk DNA.

Q: (11) If you design a gRNA with the sequence, GGU AUC AUU GCA CUG ACC AG, in theory which position of…

A:

Q: Can you please describe the organization of a typical eucaryotic gene.

A: The expressed exons and intervening introns, as well as the 5' non-coding regions essential for RNA…

Q: Define copy number variation

A: Genetics is a branch of science that deals in the study of genes, heredity, and genetic variation of…

Q: dentify and define three sections of the eukaryotic gene.

A: A gene is a structural and functional unit of heredity. Gene is made up of DNA. It is that region of…

Q: ations.

A: SNPs is single nucleotide polymorphism ,these are positions in genome where some individuals have…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.