For each of the following, describe the path the protein takes to its final destination in the cell. Drawings are strongly recommended! If you need more space, you can use a separate sheet of paper. Proteins: 1) Hedgehog (released from the signaling cell), 2) Smoothened, 3) Ci/Gli Your answers should include the following if they apply for each protein: o Sorting sequences and how the protein knows where to go at each step (what recognizes different sorting sequences/tags). How/when the protein is inserted into the membrane (if it is a membrane protein) What organelles the protein passes through on its way to its final destination. How the protein is transported (vesicles? translocons? etc.), including a role for microtubules.How the protein might be modified in each organelle it passes through. What other proteins are involved in transport and how the system is reset to allow for other proteins to be transported.
For each of the following, describe the path the protein takes to its final destination in the cell. Drawings are strongly recommended! If you need more space, you can use a separate sheet of paper. Proteins: 1) Hedgehog (released from the signaling cell), 2) Smoothened, 3) Ci/Gli Your answers should include the following if they apply for each protein: o Sorting sequences and how the protein knows where to go at each step (what recognizes different sorting sequences/tags). How/when the protein is inserted into the membrane (if it is a membrane protein) What organelles the protein passes through on its way to its final destination. How the protein is transported (vesicles? translocons? etc.), including a role for microtubules.How the protein might be modified in each organelle it passes through. What other proteins are involved in transport and how the system is reset to allow for other proteins to be transported.
For each of the following, describe the path the protein takes to its final destination in the cell. Drawings are strongly recommended! If you need more space, you can use a separate sheet of paper. Proteins: 1) Hedgehog (released from the signaling cell), 2) Smoothened, 3) Ci/Gli Your answers should include the following if they apply for each protein: o Sorting sequences and how the protein knows where to go at each step (what recognizes different sorting sequences/tags). How/when the protein is inserted into the membrane (if it is a membrane protein) What organelles the protein passes through on its way to its final destination. How the protein is transported (vesicles? translocons? etc.), including a role for microtubules.How the protein might be modified in each organelle it passes through. What other proteins are involved in transport and how the system is reset to allow for other proteins to be transported.
For each of the following, describe the path the protein takes to its final destination in the cell. Drawings are strongly recommended! If you need more space, you can use a separate sheet of paper. Proteins: 1) Hedgehog (released from the signaling cell), 2) Smoothened, 3) Ci/Gli Your answers should include the following if they apply for each protein: o Sorting sequences and how the protein knows where to go at each step (what recognizes different sorting sequences/tags). How/when the protein is inserted into the membrane (if it is a membrane protein) What organelles the protein passes through on its way to its final destination. How the protein is transported (vesicles? translocons? etc.), including a role for microtubules.How the protein might be modified in each organelle it passes through. What other proteins are involved in transport and how the system is reset to allow for other proteins to be transported.
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