what is the difference between a ligand and a domain? I understand they both attach with proteins but how do u identify which is which? Also, what is the difference between the function of the two?

Q: A lysine is on the surface of a protein, near an aspartate. How does the aspartate alter the pKa of…

A: The pKa of an amino acid's side chain determines whether it is protonated (+) or deprotonated (-)…

Q: Which of the following is the LEAST likely ER signal sequence? All sequences are written with their…

A: ER signal sequences are amino acid sequences in proteins that direct protein transport to the…

Q: What characteristics of a binding site determine its affinity for a ligand?

A: The binding site is a region where the upcoming molecule like any ligand/substrate (smaller in size)…

Q: For a protein that binds multiple ligands with negative cooperativity, which of the following is…

A: The ligand binds to its target molecule

Q: What do the complementary shapes of the ligand and the protein-binding site determine?

A: Ligands are molecules with which proteins interact via various bonds and forces. It can be an…

Q: Which of these situations would produce a Hill plot with a Hill coefficient less than 1? A purified…

A: A Hill plot is used to establish the cooperativity of ligand binding to a protein.NH (Hill…

Q: How do you think incorporating b-homoserine into a peptide would affect the structure and/or…

A: Homoserine, is the product of a cyanogen bromide cleavage of a peptide by degradation of methionine.…

Q: Peptide #1:  L-I-T-V Peptide #2:  C-Q-H-R Peptide #3:  E-G-E-A   Which peptide is the most basic?…

A: Amino acids are the building blocks of protein. An amino acid contains a carboxylic acid and a-amino…

Q: Draw the fractional binding curve with protein that bind to a molecule of ligand L.

A: A ligand is a molecule that binds to a receptor. The specificity of the ligand varies. One ligand…

Q: What does the affinity of a binding site for a ligand determine?

A: A substance that forms a complex with the biological molecule to perform a particular function. In…

Q: 1) A ligand-binding protein showing negative homotropic cooperativity? a) should give an nH value…

A: Cooperativity or cooperative binding occurs when binding of one molecule influences the affinity of…

Q: Peptides can be separated according to their charges via an ion-exchange column. In a…

A: Ion exchange chromatography is used to separate molecules based on the charge. Anion and cation…

Q: Two proteins bind the same ligand, and the data is shown below. Select the best answer based on this…

A: A single biomolecule's 2binding affinity is the potency of the binding relationship with its ligand…

Q: You've got a solution containing 60 μM VIP (very important protein). VIP binds to its ligand L with…

A: Ligand-protein interactions are best described by their Dissociation Constants (KD). Let us…

Q: What are the A site and the P site? How are their roles in protein synthesis similar? How do they…

A: The protein is a principle component of all the cell. It is an organic compound that is made of one…

Q: What do you understand by binding-change mechanism?

A: The binding change mechanism is involved in ATP synthesis. This mechanism is developed by Paul…

Q: What is the most consistently (i.e. found in every case) energetically unfavorable aspect of protein…

A: People have developed molecular dynamics simulations of the basic atomic forces that determine a…

Q: Sort the following events to reflect the order in which they should occur during vesicle docking…

A: Answer correct option (b) 3124 Vesicle have bounded Rab-GTP which interacts with Rab effector…

Q: How can I distinguish between orthosteric, allosteric and cryptic ligand binding sites?

A: A binding site is a specific area on a macromolecule like a protein that binds to another molecule.…

Q: What is meant by the binding problem, and what is necessary for binding to occur?

A: "The Binding Problem" is one of the most well-known open questions in computational neuroscience.…

Q: What is cooperative binding and how can I distinguish positive and negative cooperativity? How does…

A: Enzymes are the biological catalysts that alter the rate of the reaction. This enzymes has specific…

Q: What are the possible phosphorylation sites in a target protein?

A: Protein phosphorylation It is defined as the process of reversible post translational modification…

Q: What are the Characteristics Binding Site?

A: Binding sites are present in all the macromolecules such as proteins. This binding is done with…

Q: Where will the amino (NH2) terminus of the protein be located (cytosol vs. ER lumen) if the “start”…

A: The endoplasmic reticulum is a cell organelle which is an extension of the nuclear envelope. Its…

Q: What do you name the binding between two amino acids?

A: An organic molecule comprised of a carboxyl and an amino group is known as amino acids. When amino…

Q: When a globular cytoplasmic protein folds into its proper tertiary structure, which of the following…

A: Globular proteins are somewhat water-soluble proteins. These are usually spherical in shape.

Q: The following sequence is a portion of the N-terminus of the ACE2 receptor.  The secondary structure…

A: Each amino acid has a different property.

Q: Glycopeptide X is composed of a glycan Y and an octapeptide. The octapeptide was cleaved by trypsin,…

A: Trypsin and chymotrypsin are the proteases that break down protein into individual amino acids.…

Q: Which of the following sequences represents a recognition site for N-linked glycosylation where X is…

A: N-linked glycosylation, is the attachment of an oligosaccharide,  sometimes also referred to as…

Q: I'm working on the thermodynamics of protein binding but I want to understand more on the enthalpic…

A: Introduction Protein folding and protein-ligand interaction are basically thermodynamically driven…

Q: Two proteins bind the same ligand, and the data is shown below. What is the KD value for Protein B?…

A: The answer of the above question is: Correct answer not given. KD is the equilibrium dissociation…

Q: What types of amino acids are the least likely to be found in the center of a transmembrane protein?…

A: Biomolecules are organic molecules present in living organisms. Proteins are one of the major…

Q: Erk and P-Erk live in two different locations within the cell even though they are just two…

A: * Mitogen activated protein kinase also called as  MAPK and  p42MAPK, and ERK2 * It is an enzyme…

Q: The primary function of chaperones is to ... Select an answer and submit. For keyboard navigation,…

A: Chaperones are the proteins that facilitate the proper folding of the proteins. These proteins are…

Q: Which are the Three binding sites with the same chemical specificity but different affinities for a…

A: Proteins are the polymers of the amino acids. Here, amino acids are connected by peptide bonds.…

Q: The properties of a side chain can be affected by its microenvironment, or the environment that is…

A: Pka of an Amino acid is the measure of strength of an acid . Acid with less pka value of less than…

Q: About

A: Protein synthesis is important for performing various functions in the body. Synthesis of protein…

Cell Signaling

It allows cells to perform various cellular activities, coordinate, and interact with other cells. All cells of an organism receive signals from their environments and respond accordingly. Even the unicellular eukaryotes receive signals secreted by other cells and respond. In the case of yeast, mating takes place by signaling between the yeast cells. Communication by cell signaling in a multicellular organism has become a vast and important part of various fields of biology.