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A: the difference between virus and bacteriophage
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Explain the main defects of using animal models for viral growth and cultivation.
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- discuss the benefits and limitations of using a retroviral system or an adenovirus for the delivery of a therapeutic gene.Discuss the principles behind the use of the following techniques in the diagnosis of viral infections, providing examples of viruses diagnosed using these methods 5..1 ELISA 5.2 Restriction Fragment Length Polymorphism 5.3 Polymerase chain reactionDiscuss the advantages and disadvantages of the use of the following viruses as vectors a. Retroviruses b. Adenoviruses c. Adeno-associated viruses
- Explain the mechanism by which some (+)ssRNA viruses are able to produce many proteins from a single RNA.. a. Compare the means by which retroviral and AAVvectors deliver therapeutic genes to human cells.b. Explain the advantages and disadvantages of eachof the two viral vectors.Discuss some advantages and disadvantages of bacteriophage therapyin treating bacterial infections.