Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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- Draw and analysis of
DNA replication at one replication fork. Show how the leading and lagging strands are synthesized and the proteins (enzymes) involved in DNA replication and what their functions are
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- Arrange the steps of DNA replication in the order that they occur. First step Helicase unwinds the DNA double helix. Last step Answer Bank DNA polymerase synthesizes DNA. RNA primers are added. DNA ligase joins DNA fragments together. RNA primers are removed. Single-stranded DNA-binding proteins bind to each template strand.arrow_forwardDescribe the structure of a bacterial genome, and explain how it differs from a eukaryotic genome. Explain what a plasmid is, and describe the role of plasmids in the spread of antibiotic resistance genes. Explain how bidirectional semiconservative DNA replication copies the circular chromosome of a bacterium during cell division. Explain the steps of replication by DNA polymerase, including initiation, elongation, and termination. Explain the different kinds of mutations and how they occur.arrow_forwardwhat if a mutation resulted in the enzyme DNA polymerase III being non-functional? How would that affect DNA replicationarrow_forward
- List and describe the important proteins involved in transcription (that are found around the replication fork).arrow_forwardA. DNA Replication Construct a DNA with 15 base pairs. (Note that the first three nucleofides of the parent DNA (3' to 5') strand correspond to a start codon and its last three nucleotides correspond to a stop codon in its MRNA counterpart later on.) Write it down as follows: a. the sequence of parent DNA (template) 3' A C A TT 5' 3' Upon undergoing DNA replication, show what one daughter DNA molecule will look like. Write it down as follows: b. the sequence of DNA Daughter 1: 3' 5' 5' 3' C. the sequence of DNA Daughter 2: 3' 3' 5' in inarrow_forwardGive only typing answer with explanation and conclusion You are studying a strain of bacteria that carries a temperature-sensitive mutation in one of the genes required for DNA replication. The bacteria grow normally at the lower temperature, but when the temperature is raised they die. When you analyze the remains of the bacterial cells grown at the higher temperature you find evidence of partly replicated DNA. When the strands of this DNA are separated by heating, numerous single-stranded DNA molecules around 1000 nucleotides long are found. Which of the proteins listed below are most likely to be impaired in these mutant bacteria and why?: Primase, Helicase, or DNA Polymerase?arrow_forward
- Give typed full explanationarrow_forwardDuring DNA replication, 3 different proteins are used in the process to unwind and seperate the DNA. What are these 3 proteins and is there an helpful way that can I remember what each of thier functions are?arrow_forwardDescribe, in detail, causes for mutations that occur during replication. For each, use detail to describe how the mutation would occur, classify the type of mutation that results, and the effect it may have on the cell. What are two causes for mutations during replication? What is one cause for mutations at the end of replication? Differentiate between transition and transversion mutations. What are they, examples? How do point deletions/insertions lead to frameshift mutations- your answer should include what a “frame” is, what a codon is and how codons are responsible for making aa chains?arrow_forward
- use the terms RNA primase dna polymerase helicase leading strand and lagging strand to briefly describe how DNA replicatesarrow_forwardDuring DNA replication: A. The two DNA strands separate, each strand then becomes a template for the assembly of a complementary strand. Each new DNA helix has one old strand with one new strand. B. The two DNA strands separate, each strand then becomes a template for the assembly of a similar strand. Each new DNA helix has one old strand with one new strand. C. The two DNA strands separate, each strand then becomes a template for the assembly of a similar strand. Each new DNA helix has two new strands. D. The two DNA strands separate, each strand then becomes a template for the assembly of an identical strand. Each new DNA helix has one old strand with one new strand.arrow_forwardBelow is a study of a colony of cells, determine that some of these cells have a mutated DNA polymerase I that results in loss of function of this enzyme. - What will the effect of the mutation in DNA polymerase I be on DNA replication? Include leading and lagging strand - Will this mutation in DNA polymerase I have an impact on another step in DNA replication? Will DNA be replicatation be impacted? Are any enzymes involved?arrow_forward
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