Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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- What are the products of the following transamination reaction? a-ketoglutarate + alanine O glutamate; pyruvate none of these O aspartate; oxaloacetate O aspartate; pyruvate O glutamate; oxaloacetate How many ATP and electrons are required for the reduction of one molecule of nitrogen to two molecules of ammonia in the reaction catalyzed by nitrogenase? O 16 ATP and 6 electrons 8 ATP and 8 electrons O 16 ATP and 8 electrons 8 ATP and 16 electrons O 16 ATP and 16 electrons What enzyme is responsible for the incorporation of ammonia from nitrogen fixation into organic molecules? O transaminase glutamine synthetase O glutamate synthetase O glutamate synthase O glutamine synthase What amino acid is the precursor for the neurotransmitters epinephrine and norepinephrine? O tryptophan O serine aspartate O tyrosine O glutamate O Oarrow_forwardThe oxidation of Gly-3-P to 1,3-bisphosphoglycerate proceeds with an unfavorable AG which equals 6.3 KJ/mol, yet the flow through this point in the glycolytic pathway proceeds smoothly. Why???arrow_forwardCan someone help with this question?arrow_forward
- Propose a pathway for the following compound to enter gluconeogenesis / glycolysis. In your pathway, include enzymes (you can use E1, E2, etc.) as well as any necessary cofactors.arrow_forwardWhat glycolytic intermediate is fructose converted to in the muscle, such that it can be utilized in glycolysis? Glucose 6-phosphate Fructose 6-phosphate Glyceraldehyde 3-phosphate Dihydroxyacetone phosphatearrow_forwardWhy does it make good metabolic sense for phosphoenolpyruvate carboxykinase, rather than pyruvate carboxylase, to be the primary target for the regulation of gluconeogenesis at the level of control of enzyme synthesis? Match the words in the left column to the appropriate blanks in the sentences on the right. fructose-1,6-bisphosphate pyruvate 3-phosphoglycerate increasing reducing glycolytic pathway forward acetaldehyde lactate phosphoenolpyruvate oxaloacetate citric acid cycle back glyceraldehyde- 3-phosphate Firstly, pyruvate carboxylase converts which can participate in the gluconeogenesis pathway, and also plays an additional metabolic role in aiding the entry of intermediates into the Hence, it makes sense for phosphoenolpyruvate carboxykinase (PEPCK) to catalyze the conversion of gluconeogenesis pathway , thereby pyruvate carboxylase. to to Thirdly, PEPCK action results in the formation of amino acids and their subsequent entry into the citric acid cycle. Reset Help to push the…arrow_forward
- The first step of gluconeogenesis involves the carboxylation of pyruvate and has a large negative delta G (i.e very exergonic). Explain how it is possible that this step can be exergonic if we know that adding CO2 onto molecules is fundamentally a destabilizing phenomenon?arrow_forwardA sample of glycogen from a patient with liver disease is incubated with Pi, normal glycogen phosphorylase, and normal debranching enzyme. The ratio of glucose 1-phophate to glucose in the reaction mixture is 100. What is the patient’s most likely enzymatic deficiency?arrow_forwardConsider the following reaction of the glycolysis pathway. Which statement is NOT true regarding this reaction? P + C-H NADH + H+ NAD+ C-0-P H-C-OH H-C-OH Glyceraldehyde- CH₂0-P 3-phosphate dehydrogenase CH₂0-P 1,3-Bisphosphoglycerate Glyceraldehyde-3- phosphate O A one-carbon compound (1C) is converted into a two-carbon compound (2C). O It requires a coenzyme. O It is a redox reaction catalyzed by the enzyme glyceraldehyde-3-phosphate dehydrogenase. O It is a phosphorylation reaction.arrow_forward
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