a-ketoglutarate H + NADPH • NH, #1 NADP glatamate dehydrogenase ATP + H + NADPH ADP + NADP + P glutamate (glutamic acid) a-semialdehyde #2b elatamate kinase dehydrogenase #3 ATP + NH. #2a (spontaneous) glatamate synthetase ADP + P.+ H Text glutamine A'-pyrrolidine 5-carboxylate r + NADPH #4 NADP pyrrolidine carbaxylate reductase proline

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter27: Metabolic Integration And Organ Specialization
Section: Chapter Questions
Problem 5P
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 Are there any steps that have phosphorylation/dephosphorylation, hydration/dehydration ,or hydrolysis reactions? If so, which are they?

a-ketoglutarate
H* + NADPH + NH,
#1
NADP +
glutamate dehydrogenase
ATP + H* + NADPH
ADP + NADP
+ P.
glutamate
a-semialdehyde
(glutamic acid)
NH
# 2b
glutamate kinase dehydrogenase
# 3
ATP + NH
#2a
(spontaneous)
glutamate synthetase
ADP + P, +H +
Тext
glutamine
A'-pyrrolidine 5-carboxylate
H* + NADPH
# 4
NADP
pyrrolidine carbaxylate
reductase
NH
proline
Transcribed Image Text:a-ketoglutarate H* + NADPH + NH, #1 NADP + glutamate dehydrogenase ATP + H* + NADPH ADP + NADP + P. glutamate a-semialdehyde (glutamic acid) NH # 2b glutamate kinase dehydrogenase # 3 ATP + NH #2a (spontaneous) glutamate synthetase ADP + P, +H + Тext glutamine A'-pyrrolidine 5-carboxylate H* + NADPH # 4 NADP pyrrolidine carbaxylate reductase NH proline
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