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Compare and contrast the mode of action of tetanus and botulinum toxins.
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- What drugs would you recommend for Tetanus treatment? Explain the mechanism of action of the toxin from Clostridium botulinum. How this mechanism can be used for clinical and cosmetic purposes, including treatment of facial wrinkles?Abimbola's great grandfather was a member of the Fore tribe of Papua New Guinea that practiced cannibalism. He would often burst into laughter and have the shakes. He had Kuru. c) Describe the aetiologic agent of Kuru d) Discuss management and prevention of Kuru.Contrast Streptococcal toxic shock syndrome from Staphylococcal toxic shock syndrome.
- Both C. tetani and C. botulinum produce neurotoxins as VFs. Differentiate the effect of the toxin and how this leads to different types of paralysis in these diseases.Compare and contrast toxin production and toxemia inbotulism and perfringens food poisoningAccount for the fact that boiling does not destroy botulism spores but does inactivate botulinum toxin.
- Many antibiotics used in modern medicine are compounds made by fungi that inhibit bacterial protein synthesis. Describe the specific effect of the following antimicrobial drugs: (i) Chloramphenicol (ii) RifamycinCompare and contrast the actions of amoxicillin, azoles, macrolides, and polymyxin.Explain why C. tetani can be cultivated from wounds in the absence of tetanus.
- Identify the causative agent of staphylococcal food poisoning and explain the method for transmission of the bacteria to food sources. Describe the characteristics of the staphylococcal toxin.list 3 different mechanisms of antibacterial drugs. Example: acting on cell wall, cell membrane, etcWhat makes bacterial diseases such as Clostridium botulinum, Clostridium perfringens & Clostridium tetani very effective to cause infection in a human host?