Which of the following is an example of chromatin modification that stimulates gene expression? Group of answer choices A. alternative exon splicing b. microRNA binding to mRNA c. DNA methylation D. histone acetylation
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Which of the following is an example of chromatin modification that stimulates gene expression?
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- Some drugs may reduce DNA methylation at the promoter of the reelin gene. What is the likely impact that this has on reelin expression? Group of answer choices: increased transcription decreased transcription no change in transcription, but decrease in translation no effect on transcription, but increase in translation altered pattern of DNA replicationWhich of the following is a method through which cells can control their gene expression? Increase a gene's stability using post-translational modifications Epigenetic modifications of the DNA or histones to regulate DNA avilability phosphorylation of thymidines formation of crosslinks between the DNA strands and the histonesSelect the processes that only happen inside the nucleus of a eukaryotic cell. Select all that apply. O making tRNA O transcribing rRNA O removing introns from precursor mRNA O transcriptional initiation at the promoter O adding the polyA tail O mRNA binding to the small ribosomal subunit ORNA splicing O tRNA binding to codons
- Which process is the result of the post transcriptional modification of mRNA? Group of answer choices removal of exons and joining of introns that will exit nucleus transcription of DNA & RNA polymerase protection of 5’ cap & 3’ poly-A tail replication of helicase and gyraseEukaryotic transcriptional repressors may act by Choose an answer below competing for a binding site of an activator. blocking the DNA binding domain of an activator. blocking the activation domain of an activator. recruiting a histone deacetylase the action of which leads to chromatin compaction. all of the aboveWhich of the following is not a control of gene transcription? The repression of a gene by the binding of a transcription factor to a silencer region Methylation of promotor sequences The stabilization of the initiation complex by transcription factors to allow RNA polymerase to begin replication The conversion of heterochromatin to euchromatin through histone demethylation The binding of an inhibitory protein to the 3' UTR
- Shown below is an eukaryotic gene. Assuming normal wild type RNA processing in a.cell, which of the following mature MRNAS could result in normal levels of functional synthesized proteins? Select all that apply Direction of transcription Promoter Template strand 5' Exon 4 Intron 3 Exon 3 Intron 2 Exon 2 Intron 1 Exon 1 3' 5' Coding strand Transcription start Transcription start 5' CAP-Exon1-Exon3-Exon4-AA..AAAA 5' CAP-Exon1-Exon2-Exon3-Exon4-AA...AAAA 5' CAP-Exon1-Exon2-Exon3-Exon4 Exon1-Exon2-Exon3-Exon4-.....AAAAe table below with the word that matches the definition in the right column. regulatory proteins (transcription factors) that speed up transcription by helping RNA polymerase bind to a promoter DNA sequences that indicate where transcription of a gene by RNA polymerase begins-typically located upstream from the 5C end Proteins bound to DNA that affect when and how fast a gene is transcribed These factors slow down/shut off transcription either by preventing access to promoters or by keeping RNA polymerase from moving along the DNA strand 3 Regulatory DNA sequénces located upstream or downstream from an associated gene that enhance the transcription rate of that gene when bound to specific proteins 3A sequence of DNA that when bound to a transcription factor blocks the inappropriate effect of an enhancer on a neighboring geneWhich of the following mechanisms may create multiple mRNAsfrom the same gene?a. posttranslational controlb. alternative mRNA splicingc. binding of a transcription factord. chromatin remodelinge. miRNAs
- Post-translational control refers to: a. regulation of gene expression after transcription b. regulation of gene expression after translation c. control of epigenetic activation d. period between transcription and translationBinding of _______ to _______ in DNA can increase the rate of transcription of specific genes. a. activators; repressors c. repressors; operators b. activators; enhancers d. repressors; enhancersPut the following processes in order of their occurrence during expression of a eukaryotic gene: a. mRNA processing c. transcription b. translation d. RNA leaves nucleus
