Caffeine is a stimulant found in coffee, tea, soft drinks and other drinks and foods. After consumption, caffeine is absorbed into the blood stream and carried throughout the body and to the brain. In moderate amounts (~300 mg per day) it causes increased attentiveness, it reduces feelings of fatigue, and it enables most people to think clearly and concentrate for longer periods. Caffeine also increases heart rate and rate of respiration. In large quantities (>600 mg per day) its effects are magnified. People sometimes feel irritable, distracted and tense.   People often use caffeine to increase mental alertness. Some people are more sensitive than others to the effects of caffeine. People who consume caffeine regularly may build up a tolerance to its effects. Further, since caffeine is mildly addictive, people who regularly consume caffeine may experience some withdrawal effects if they stop consumption.   The Study In this study, three people each consumed varying levels of caffeine and recorded how they were feeling on a daily basis. Caffeine was administered at 8 am on day 1, day 2, day 3. Subjects didn’t know how much caffeine (or if any) they were consuming each day.   Day 1 – Caffeine dose: 100 mg Day 2 – Caffeine dose: 300 mg Day 3 – Caffeine dose 600 mg Subjects were asked not to consume any caffeine outside the administered dose for the three days of the study.   1. Caffeine affects several of the body’s systems. After examining the data, explain how the body systems are affected and how this relates to mechanisms of homeostasis. Researching Caffeine may aid you in your explanation.     2. Give reasons why the caffeine affected each person differently. Explain your response.     3. Give a possible explanation for Person A’s symptoms on day 1.

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Caffeine is a stimulant found in coffee, tea, soft drinks and other drinks and foods. After consumption, caffeine is absorbed into the blood stream and carried throughout the body and to the brain. In moderate amounts (~300 mg per day) it causes increased attentiveness, it reduces feelings of fatigue, and it enables most people to think clearly and concentrate for longer periods. Caffeine also increases heart rate and rate of respiration. In large quantities (>600 mg per day) its effects are magnified. People sometimes feel irritable, distracted and tense.   People often use caffeine to increase mental alertness. Some people are more sensitive than others to the effects of caffeine. People who consume caffeine regularly may build up a tolerance to its effects. Further, since caffeine is mildly addictive, people who regularly consume caffeine may experience some withdrawal effects if they stop consumption.   The Study In this study, three people each consumed varying levels of caffeine and recorded how they were feeling on a daily basis. Caffeine was administered at 8 am on day 1, day 2, day 3. Subjects didn’t know how much caffeine (or if any) they were consuming each day.   Day 1 – Caffeine dose: 100 mg Day 2 – Caffeine dose: 300 mg Day 3 – Caffeine dose 600 mg Subjects were asked not to consume any caffeine outside the administered dose for the three days of the study.   1. Caffeine affects several of the body’s systems. After examining the data, explain how the body systems are affected and how this relates to mechanisms of homeostasis. Researching Caffeine may aid you in your explanation.     2. Give reasons why the caffeine affected each person differently. Explain your response.     3. Give a possible explanation for Person A’s symptoms on day 1.     4. How could you improve this experiment in order to collect better data?     5. What are the ethical concerns with an experiment such as this and how could these be addressed?     6. What are the limitations of this experiment (eg. sample size)? How could these be addressed?   7. How does this experiment impact your decision making?   8. Pose at least one question you still have about the effects of caffeine on the human body.
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Person A
Male, 24 years old, semi-active lifestyle
Usually drinks 3-4 cups of coffee (250-350 mg caffeine) per day
Day 1 I felt pretty normal first thing this morning, but by the time I got to work I
could feel a headache coming on. The headache got worse throughout the
morning. I felt groggy all morning. It was very difficult to focus on my
work. I was tired and unmotivated.
By the end of the day my headache was down to a dull pain and I was
exhausted.
Day 2 Had a pretty good sleep last night, except for that lingering headache. The
headache was still persisting first thing this morning, but went away by
about 9:00 am. I felt normal today-an average amount of energy and a
normal level of concentration at work.
Day 3 I had a good sleep last night. Thank goodness that awful headache went
away! I woke up feeling rested. Around mid- morning my heart rate felt
a bit fast, but it leveled out after not too long. I felt alert at work: maybe
a bit too alert. I had several.
Person B
Male, 38 years old, very active
lifestyle Usually avoids caffeine
Day 19 am-increase in heart rate morning-
attentive to tasks at work afternoon-still
attentive to tasks at work
evening went to the gym and had a great workout! 11 pm
-still awake, should be sleeping by now
Day 2 7 am a bit tired; should have gone to bed earlier 9 am
hyper, increased heart rate
late morning trying to focus on one task, but keep getting
distracted
afternoon feel like I haven't actually accomplished anything today-
hard to focus on finishing any one task evening-worn out, but mind
still busy
11:59pm still awake; brain won't shut off
Day 3 7am tired; had trouble sleeping 9
am-wired, shaky, racing heart
10 am irritable, upset stomach, still shaky, unable to focus on the task
at hand. I feel awful.
afternoon grouchy, tense
evening stomach feeling better, but still feel wired.
11:59 pm I can't get comfortable and my mind is still racing. This is
going to be a long night!
Person C
Female, 18 years old, semi-active lifestyle
Rarely drinks coffee, but drinks cola (50 mg caffeine) at least
once a day.
Day 1 I felt pretty normal all day.
Day 2
Shortly after the dose, I felt an increase in heart rate. I had a
productive day of studying great focus! Stayed up a bit later than
normal.
Day 3 After the dose my heart was racing and I felt a bit shaky. Not such
good focus today; my mind was all over the place. By the evening I
was less shaky, but my mind was still busy and I was up late again.
Transcribed Image Text:0 Person A Male, 24 years old, semi-active lifestyle Usually drinks 3-4 cups of coffee (250-350 mg caffeine) per day Day 1 I felt pretty normal first thing this morning, but by the time I got to work I could feel a headache coming on. The headache got worse throughout the morning. I felt groggy all morning. It was very difficult to focus on my work. I was tired and unmotivated. By the end of the day my headache was down to a dull pain and I was exhausted. Day 2 Had a pretty good sleep last night, except for that lingering headache. The headache was still persisting first thing this morning, but went away by about 9:00 am. I felt normal today-an average amount of energy and a normal level of concentration at work. Day 3 I had a good sleep last night. Thank goodness that awful headache went away! I woke up feeling rested. Around mid- morning my heart rate felt a bit fast, but it leveled out after not too long. I felt alert at work: maybe a bit too alert. I had several. Person B Male, 38 years old, very active lifestyle Usually avoids caffeine Day 19 am-increase in heart rate morning- attentive to tasks at work afternoon-still attentive to tasks at work evening went to the gym and had a great workout! 11 pm -still awake, should be sleeping by now Day 2 7 am a bit tired; should have gone to bed earlier 9 am hyper, increased heart rate late morning trying to focus on one task, but keep getting distracted afternoon feel like I haven't actually accomplished anything today- hard to focus on finishing any one task evening-worn out, but mind still busy 11:59pm still awake; brain won't shut off Day 3 7am tired; had trouble sleeping 9 am-wired, shaky, racing heart 10 am irritable, upset stomach, still shaky, unable to focus on the task at hand. I feel awful. afternoon grouchy, tense evening stomach feeling better, but still feel wired. 11:59 pm I can't get comfortable and my mind is still racing. This is going to be a long night! Person C Female, 18 years old, semi-active lifestyle Rarely drinks coffee, but drinks cola (50 mg caffeine) at least once a day. Day 1 I felt pretty normal all day. Day 2 Shortly after the dose, I felt an increase in heart rate. I had a productive day of studying great focus! Stayed up a bit later than normal. Day 3 After the dose my heart was racing and I felt a bit shaky. Not such good focus today; my mind was all over the place. By the evening I was less shaky, but my mind was still busy and I was up late again.
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