A researcher is curious whether 30 minutes of daily exercise can decrease the blood glucose levels back to normal in patients with Type 2 Diabetes. what is the Controlled Variable and Control group?

What units is insulin dosing ordered in?

Apply the Bonferroni correction to a study comparing two treatments. There are three independent outcomes compared at 30 days, 6 months, and at 1 and 2 years and the researchers also evaluates whether the treatments are different for patients with diabetes at 30 days and 2 years.   0.002   0.0003   0.006   0.003

Yellow: Did not have answers from anyone but confident based on notes Question 1: Insulin can have pleiotropic (wide ranging) effects in cells because...? 1. The insulin receptor phosphorylates with a family of substrates inside the cell 2. There are over 20 versions of the insulin receptor expressed in vertebrates 3. The insulin receptor heterodimers with the GH and PRL receptors 4. MRAP (membrane associated receptor proteins) couple the insulin receptor to different effector pathways Question 2: Cholecystokinin (CCK) is accurately described by which of the following statements? 1. It is not a member of the peptide hormone superfamily 2. It binds to a 1-TMS receptor that signals through guanylate cyclase 3. It is sulphated on tyrosine residues for full activity 4. It is proteolytically released from POMC by gut cells Question 3: Insulin... 1. Is released from the pancreas in vertebrates and invertebrates 2. Is released from the vertebrate pancreas in response to hyperglycemia 3. Is…

Assume you have a monoclonal antibody specific for phosphotyrosine. How do you anticipate the antibody affecting insulin signalling?

If a patient was taking 3 oral diabetes medication but their blood glucose level was not controlled what therapy would you recommend?

On Morgan Water's Oklahoma Indian reservation, one fourth of her tribe had diabetes. Of course, she knew that. Everyone had heard that. Morgan had no family history of diabetes, heart disease, or other serious conditions; she never imagined she was at any risk. However, she overlooked the fact that environmental factors as well as genetic factors play a crucial role in the development of diabetes. At the age of 27, Morgan was obese and led a sedentary lifestyle. In the past few months, she had been experiencing unusual thirst, dizziness, blurred vision, and an awkward feeling of numbness in her right foot. Following her parents' advice, she finally visited the family doctor. She was worried, but never suspected what she would hear. "I'm sorry, Morgan, but the tests I've conducted unfortunately reveal that you have Type 2 diabetes. Your symptoms are exactly like those we see in many Native Americans. You have a high blood sugar. In people who aren't diabetic, the food that is digested…

For our patient John with diabetes type II, he can make insulin but his body cells can be resistant to this insulin. Note: activated insulin receptors will activate glucose receptors. John takes a drug called metformin, in conjunction with regulating his diet and exercising. This drug has two main effects. First, it helps reduce hepatic (liver) production of glucose. Second, it helps cells become more sensitive to insulin. Explain how these two effects of metformin can help John.

Give the Prevelance of type 2 diabetes in the UK from 2010-2022. in a table format

Consider these facts. The husband weighs 130 kg (286 pounds) and the wife weighs 65 kg (143 pounds). Their servings of pufferfish each contained 0.10 mg of tetrodotoxin.      Using these data, find a method to calculate the dose of tetrodotoxin that each person received. What dose (in mg/kg) of tetrodotoxin did each receive?