By what mechanisms has S. pneumoniae developed resistance to erythromycin? Select one: O a. Mutation in the tetM gene, which leads to a confrontational change in the ribosomal subunits, preventing the antibiotic from recognising the target. O b. Alterations in the 23S FRNA target sites due to mutation in ermB gene and active drug efflux encoded by the mefE gene. O c. Mutation in the parC gene and/ or gyrA gene can prevent the antibiotic from recognising its enzyme targets. O d. None of these answers e. Alterations in the membrane proteins, leads to decreased affinity between the drug and the proteins.

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter10: Reconstitution Of Powdered Drugs
Section: Chapter Questions
Problem 4.2P
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By what mechanisms has S. pneumoniae developed resistance to erythromycin?
Select one:
O a. Mutation in the tetM gene, which leads to a confrontational
change in the ribosomal subunits, preventing the antibiotic from
recognising the target.
O b. Alterations in the 23S rRNA target sites due to mutation in ermB gene and active
drug efflux encoded by the mefE gene.
O c. Mutation in the parC gene and/ or gyrA gene can prevent the
antibiotic from recognising its enzyme targets.
O d. None of these answers
Alterations in the membrane proteins, leads to decreased
affinity between the drug and the proteins.
Transcribed Image Text:By what mechanisms has S. pneumoniae developed resistance to erythromycin? Select one: O a. Mutation in the tetM gene, which leads to a confrontational change in the ribosomal subunits, preventing the antibiotic from recognising the target. O b. Alterations in the 23S rRNA target sites due to mutation in ermB gene and active drug efflux encoded by the mefE gene. O c. Mutation in the parC gene and/ or gyrA gene can prevent the antibiotic from recognising its enzyme targets. O d. None of these answers Alterations in the membrane proteins, leads to decreased affinity between the drug and the proteins.
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