**Task #1 Mc1r alleles**: In Florida Gulf coast mice, there are two different alleles of the Melanocortin Receptor (Mcr1) gene. The sequence for both alleles is shown below. This is an internal segment of the coding (non-template) sequence of the Mcr1 gene. The reading frame is set, and you do not need to find an AUG. **M allele**: 5′ …ATC ACC AAA AAC CGC AAC CTG CAC TCG… **m allele**: 5′ …ATC ACC AAA AAC TGC AAC CTG CAC TCG… **A.** Compare these two allele sequences and circle the nucleotides that are different. **B.** Do you think this change will cause a shift in the codon reading frame? Why or why not? **C.** Do you think that this change will cause an early stop in translation? Why or why not? --- The image includes an **mRNA Codon Table** which assists in understanding the translation of mRNA codons to amino acids. - **Rows and Columns**: The table is organized with the first base along the vertical axis (U, C, A, G), the second base along the horizontal axis (U, C, A, G), and the third base down the side of each sub-square. - **Codons and Amino Acids**: Each combination within the table shows the corresponding amino acid or stop signal in the mRNA translation process. - **Stop Codons**: Indicated in the table are the codons UAA, UAG, and UGA which signal termination of protein synthesis.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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**Task #1 Mc1r alleles**: In Florida Gulf coast mice, there are two different alleles of the Melanocortin Receptor (Mcr1) gene. The sequence for both alleles is shown below. This is an internal segment of the coding (non-template) sequence of the Mcr1 gene. The reading frame is set, and you do not need to find an AUG.

**M allele**:  
5′ …ATC ACC AAA AAC CGC AAC CTG CAC TCG…

**m allele**:  
5′ …ATC ACC AAA AAC TGC AAC CTG CAC TCG…

**A.** Compare these two allele sequences and circle the nucleotides that are different.

**B.** Do you think this change will cause a shift in the codon reading frame? Why or why not?

**C.** Do you think that this change will cause an early stop in translation? Why or why not?

---

The image includes an **mRNA Codon Table** which assists in understanding the translation of mRNA codons to amino acids.

- **Rows and Columns**: The table is organized with the first base along the vertical axis (U, C, A, G), the second base along the horizontal axis (U, C, A, G), and the third base down the side of each sub-square.
- **Codons and Amino Acids**: Each combination within the table shows the corresponding amino acid or stop signal in the mRNA translation process.
- **Stop Codons**: Indicated in the table are the codons UAA, UAG, and UGA which signal termination of protein synthesis.
Transcribed Image Text:**Task #1 Mc1r alleles**: In Florida Gulf coast mice, there are two different alleles of the Melanocortin Receptor (Mcr1) gene. The sequence for both alleles is shown below. This is an internal segment of the coding (non-template) sequence of the Mcr1 gene. The reading frame is set, and you do not need to find an AUG. **M allele**: 5′ …ATC ACC AAA AAC CGC AAC CTG CAC TCG… **m allele**: 5′ …ATC ACC AAA AAC TGC AAC CTG CAC TCG… **A.** Compare these two allele sequences and circle the nucleotides that are different. **B.** Do you think this change will cause a shift in the codon reading frame? Why or why not? **C.** Do you think that this change will cause an early stop in translation? Why or why not? --- The image includes an **mRNA Codon Table** which assists in understanding the translation of mRNA codons to amino acids. - **Rows and Columns**: The table is organized with the first base along the vertical axis (U, C, A, G), the second base along the horizontal axis (U, C, A, G), and the third base down the side of each sub-square. - **Codons and Amino Acids**: Each combination within the table shows the corresponding amino acid or stop signal in the mRNA translation process. - **Stop Codons**: Indicated in the table are the codons UAA, UAG, and UGA which signal termination of protein synthesis.
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