Below is a diagram of a gene that is not normally alternatively spliced. All four exons (represented as boxes) are found in the mature mRNA. Transcription starts at the arrow labeled TSS, transcription stops at the line labeled TT, and the promoter location is indicated by the line. The indicated DNA sequences for two individuals are found within exon 2 as indicated, with Individual 2 having a mutation. Both sequences are in-frame with the upstream start codon. ATG TAA Promoter (Start codon) (Stop codon) TSS TT Individual 1 5' ACAGGAGGAATAAGTTATGCA 3' Individual 2 5' ACAGGAGGAATAAGTTAAGCA 3' Part 1 You isolate the mature mRNAs for each individual and run them on a northern blot. Compared with the MRNA for Individual 1, you find that the mRNA for Individual 2 is more abundant. the same length. shorter. alternatively spliced. longer. Co0 000
Below is a diagram of a gene that is not normally alternatively spliced. All four exons (represented as boxes) are found in the mature mRNA. Transcription starts at the arrow labeled TSS, transcription stops at the line labeled TT, and the promoter location is indicated by the line. The indicated DNA sequences for two individuals are found within exon 2 as indicated, with Individual 2 having a mutation. Both sequences are in-frame with the upstream start codon. ATG TAA Promoter (Start codon) (Stop codon) TSS TT Individual 1 5' ACAGGAGGAATAAGTTATGCA 3' Individual 2 5' ACAGGAGGAATAAGTTAAGCA 3' Part 1 You isolate the mature mRNAs for each individual and run them on a northern blot. Compared with the MRNA for Individual 1, you find that the mRNA for Individual 2 is more abundant. the same length. shorter. alternatively spliced. longer. Co0 000
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter9: Gene Expression And Gene Regulation
Section: Chapter Questions
Problem 10QP: The pre-mRNA transcript and protein made by several mutant genes were examined. The results are...
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