Base oxidation (small damage to a single nucleotide) is repaired using:

Which DNA repair mechanisms makes use of recombination between a damaged strand of a DNA molecule and an undamaged strand? Group of answer choices postreplication repair nucleotide excision repair antioxidant repair mismatch repair all of these are DNA repair mechanisms

What type of spontaneous change to DNA is caused by UV light? deamination pyrimidine dimerization oxidative damage depurination

The holoenzyme consists of 2 DNA polymerase core enzymes single sliding clamp-loader complex two sliding clamp

Which of the following DNA repair mechanisms involves the 3' to 5' exonuciease function of DNA polymerase? mismatch repair postreplication repair SOS response DNA proofreading base excision repair

Remdesivir is an antiviral drug used to treat SARS-CoV-2 infections. It is a broad-spectrum antiviral, meaning it has activity against many different viruses. Remdesivir can be incorporated into a new RNA chain as a virus replicates and can interfere with the viral replication machinery. Template RNA Elongation New RNA SARS-CoV-2 RNA polymerase Template groove Nucleotide entrance Nucleotides Remdesivir Figure 1. A representation of remdesivir and the viral replication machinery for SARS-CoV-2. 6. Figure 1 shows that remdesivir "mimics” an important component of RNA replication. Which specific component of RNA replication has a structure like that of remdesivir? 7. Propose a hypothesis about how remdesivir might inhibit the virus's replication process.

Polymerase chain reaction cannot amplify complete circular plasmids. True False

Which of the following DNA repair pathways repair DNA double strand breakage that only occur in dividing cells? Please select ALL correct answer options. Synthesis-dependent strand annealing (SDSA) Double-strand break repair (DSBR) Nucleotide excision repair (NER) Non-homologous end joining (NHEJ) Mismatch repair (MMR)

A group of unstable DNA polymerases that produce short DNA sequences when the normal polymerase cannot function appropriately.    DNA intercalating Polymerases Bypass Polymerases Transversion Polymerases Homolgous Recombination Polymerases