Figure 1. A representation of remdesivir and the viral replication machinery for SARS-CoV-2. 6. Figure 1 shows that remdesivir "mimics" an important component of RNA replication. Which specific component of RNA replication has a structure like that of remdesivir? 7. Propose a hypothesis about how remdesivir might inhibit the virus's replication process.

Answered: Figure 1. A representation of remdesivir and the viral replication machinery for SARS-CoV-2. 6. Figure 1 shows that remdesivir "mimics" an important component…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN: 9780134580999

Author: Elaine N. Marieb, Katja N. Hoehn

Publisher: PEARSON

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Concept explainers

Viral Replication

The virus is acellular and considered non-living outside the host cell. The replication of the virus occurs only inside the living cells. Only a few genes are present in the smallest virus, whereas many genes are present in the largest virus. These genes…

Question

100%

Remdesivir is an antiviral drug used to treat SARS-CoV-2 infections. It is a broad-spectrum antiviral, meaning it
has activity against many different viruses. Remdesivir can be incorporated into a new RNA chain as a virus
replicates and can interfere with the viral replication machinery.
Template RNA
Elongation
New RNA
SARS-CoV-2 RNA polymerase
Template groove
Nucleotide
entrance
Nucleotides
Remdesivir
Figure 1. A representation of remdesivir and the viral replication machinery for SARS-CoV-2.
6. Figure 1 shows that remdesivir "mimics” an important component of RNA replication. Which specific
component of RNA replication has a structure like that of remdesivir?
7. Propose a hypothesis about how remdesivir might inhibit the virus's replication process.

Expert Solution

Step 1 Introduction:

Remdesivir is an antiviral drug used for the treatment of SARS-CoV-2 infections. Its antiviral activity has been attributed to its ability to mimic a critical component of RNA replication.