(b) Describe or draw the response you would observed in cell C if an action potential occurred in cel B, closely followed by an action potential in cell A. = glutamate = AMPA receptor = GABA, receptor = GABA

what is a receptor and give one example of where a receptor is found, explaining its role is in monitoring homeostasis

Based on your knowledge of signal transduction downstream of G-protein coupled receptors, describe the pathway by which sulcatone may cause an action potential?

Mr PL was administered Drug A that acts on a particular receptor. Unfortunately, it was given in overdose and produced an adverse effect. Drug B is then administered which blocks that receptor. The effect of drug B results in a reduction in the effect of drug A. Comment on if Drug B is acting competitively (reversibly) or non-competitively (irreversibly)? Provide one suitable clinically relevant example of such interaction.

Describe the biochemical signaling steps by which activation of the NMDA receptor causes the postsynaptic cell to fire larger EPSPs.

Describe and explain in detail the effects of glutamate when it binds to postsynaptic AMPA receptors vs the effect of it when it binds to NMDA receptors.

Fill in the diagram, your illustration should demonstrate for each phase of the AP: 1. The relative concentration of K and Na 2. The relative voltage across the membrane 3. Any movement across the membrane of K and NA 4. The three kinds of channels in the membrane, and their state (open or closed) 5. Finally, indicate on the graph of the AP which phases correspond to hyper- polarization and which phases correspond to de- polarization Outside Outside Inside Inside Outside Inside Outside 1 Outside Inside Inside

Part A Which of the following statements about pain-relief substances is correct? View Available Hint(s) O Endorphins are synthetic pain-killers. O Met-enkephalin has pain-killing ability because of its structural similarity to morphine. O Many natural pain-killing polypeptides are ideal for medical use. O Receptors of opium derivatives are found in all body cells. Submit

Phospholipase C cleaved the membrane lipid PIP2 into IP3 and DAG in response to which type of membrane receptor being activated?