Mr PL was administered Drug A that acts on a particular receptor. Unfortunately, it was given in overdose and produced an adverse effect. Drug B is then administered which blocks that receptor. The effect of drug B results in a reduction in the effect of drug A. Comment on if Drug B is acting competitively (reversibly) or non-competitively (irreversibly)? Provide one suitable clinically relevant example of such interaction.

Q: b) scorpion, he felt numbness in his fingers due to the neurotoxin produced by the scorpion which is…

A: Scorpion Venom would affect the duration and amplitude of an action potential.

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Q: Serotonin is the natural ligand for the serotonin receptor. I've circled the important binding…

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Q: Which one of the cannot be considered a criterion when identifying a small neurotransmitter (NT)? 18…

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A: Sensory receptors are specialized cells or structures in the body that detect and respond to…

Q: The Structure of the acetylcholine receptor is shown below:   D. Briefly indicate what the role of…

A: Acetylcholine is a neurotransmitter at various synapses, nerves, and at the motor endplate of…

Q: A neurotransmitter that binds to a G-protein-linked receptor, such as a biogenic amine, that…

A: The question revolves around the concept of neurotransmission, specifically focusing on the role of…

Q: The one-way propagation of action potentials away from the original site of activation is ensured by…

A: Introduction: A sudden rise and thereafter a subsequent reduction in the membrane potential or…

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A: Binding of certain molecules at their receptors involves the eliciting of response that can be…

Q: 3) You are investigating the ionic selectivity of an ion channel opened by activation of a specific…

A: A.                                   E(K+)= RTnFlnOUTIN=8.314×2981×96485ln5140=-0.089≈-89mV…

Q: What is the mechanism by which voltage-gated channels open in response to voltage changes? Choose…

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Q: i) After the first stimulus, how does the excitatory postsynaptic potential (EPSP) you record from…

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Q: prevent (3pts) Chelators are compounds that bind tightly to specific ions an eliciting a biochemical…

A: Chelators are molecules that bind to metal ions and help to facilitate the transport of them across…

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A: The reward pathway, also known as the mesolimbic dopamine system, is a complex network of brain…

Q: Nicotinic ACh receptor (LGIC) involve the movement of what ion across the membrane? Group of answer…

A: Nicotinic Acetylcholine receptors are a type of ligand-gated ion channels involved in neuromuscular…

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A: * Voltage gated potassium channels are transmembrane proteins that opens in response to…

Q: a.) b.) c.) d.) +20 mV +20 mV +20 mV +20 mV FE ↑ ↑ ↓ ↑ X+ Fc ↑ ↑ flux FE ↑ ↑ ↑ ↑ ↑ Y+ Fc flux ↑ ↑ 个…

A: Ion influxes at membrane potentials refer to the movement of ions across the cell membrane in…

Q: If the neurotransmitter released by the presynaptic axon is dopamine and the diffusion distance…

A: Dopamine is a brain neurotransmitter that facilitates communication between individual neurons in…

Q: 3.) Signals are passed from axon to axon when neurotransmitter molecules are released from the…

A: Dopamine is a brain neurotransmitter that facilitates communication between individual neurons in…

Q: Suppose cells A and B, both of which release inhibitory transmitter, are endogenously tonically…

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Q: Give an example of presynaptic inhibition. Describepresynaptic facilitation.

A: Inhibition can be applied both at the presynapse and the postsynapse. An inhibitory input into a…

Q: Explain the following; If a drug partly blocks a membrane’s potassium channels, how…

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Q: Which of the following is NOT a weakness of the Meyer Overton theory? does not predict how…

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Q: Would you classify NMDA receptors as ionotropic ormetabotropic? Why?

A: Metabotropic receptors are receptors to which a non-ionic ligand binds and it will open a G-protein…