Arachidonic (AA) acid is an important lipid involved in the production of inflammatory mediators such as prostaglandins. A common treatment of inflammatory conditions is the administration of corticosteroids. These drugs lower the expression of sPLA2. Describe how corticosteroid use leads to the lowering of prostaglandins.

Q: mechanism by which Covid-19 affects the body system

A: These are a particular group of viruses that is capable of causing minor common cold to severe…

Q: Define the following terms:a. methotrexateb. circadian rhythmsc. calmodulind. Lesch-Nyhan syndromee.…

A: Molecular biology is the study of composition, structure, and interactions of cellular molecules…

Q: Describe two features of insulin signaling that affect glucose utilization. Aβ-adrenergic response…

A: The signaling pathway of insulin transduction is a biological process by which insulin enhances the…

Q: A patient with H. pylori infection develops a gastric ulcer and is treated with omeprazole. Which of…

A: The correct answer is option D. Inhibition of H+-K+ ATPase. Omеprazolе primarily еxеrts its…

Q: Among a large number of GIT hormones only a handful have been well characterized briefly discuss…

A: GIT or gastrointestinal hormones are chemical messengers that are secreted in stomach, pancreas and…

Q: 1.(a) Describe any TWO differences between Type I and Type II hypersensitive reactions.   (b) Given…

A: Type I & Type II hypersensitive reactions are two types of immune responses that can occur in…

Q: Give the biological activities and occurrence of prostaglandins and leukotrienes.

A: The human body encounters so many dangerous and harmful substances but has the ability to fight…

Q: Explain EPHB2 receptor interaction with PDZ-binding.  Give full explanantion

A: The erythropoietin-producing hepatocellular carcinoma (Eph) receptors are the biggest known class of…

Q: what Protien ligand interacts the EPH RECEPTOR EPHB2 and what drug binds to the receptor.  give…

A: EPH RECEPTOR EPHB2 is a cell surface receptor. Eph stands for Erythropoietin-producing hepatoma. It…

Q: List examples of paracrine chemical messengers that playa role in modulating pain or are peptide…

A: paracrine chemical messenger act on adjacent cells.

Q: Explain how the hormone-receptor complex can alter theG proteins on the inner surface of the plasma…

A: Cellular signaling is the process, during which the cell respond to the extracellular environment…

Q: What is the cell found in tissues where the hormone produced leaves behind a C peptide during…

A: C-peptide is a peptide composed of 31 amino acids.

Q: What are adverse effects associated with the use of Tocilizumab and dexamethasone in COVID-19.

A: Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered virus called…

Q: Explain the influence of the chemical nature of ahormone on its transport in the blood, its removal…

A: The peptide hormones that consist of three or more amino acid residues are lipophobic as they have…

Q: How are competent cells prepared by the action of CaCl2 ?

A: The bacterial cells that possess pores in their cell walls, making it easy for the cell to take the…

Q: A 47-year-old woman passes out at work and is brought to the emergency room. Her blood sugar is 24…

A: According to the question,  the patient's low blood glucose is due to excess insulin secretion…

Q: Explain why abscisic acid is sometimes referred to as astress hormone.

A: Step 1 Plant growth regulators are organic substances, excluding nutrients, which in low…

Q: Diabetes insipidus has been identified in two males. One person did not have the condition until he…

A: Diabetes insipidus is a diseases that is caused due to electrolyte imbalance in the body that can…

Q: Estrogen receptor antagonists inhibit tumors by: 1) blocking estrogen binding to receptors 2)…

A: Antiestrogens are a class of medications that stop estrogens like estradiol from mediating their…

Q: Identify A drug that has analgesic, antipyretic, and anti-inflammatory properties, which acts by…

A: Cyclooxygenase enzyme is responsible for synthesis of various biological mediators that are involved…

Q: Receptor, especially growth factor receptor signaling is deregulated in cancer cells, which results…

A: Growth Factor Receptors- These growth factors in cancer cells are also known as polypeptides which…

Q: A 10-week-old child was admitted to hospital suffering from a salt wasting crisis. Ultrasound scans…

A: In this case, the protein that is to be deficient most likely is 21-hydroxylase. It is an enzyme…

Q: Explain how aspirin can block the synthesis of prostaglandins?

A: The prostaglandins are synthesized in every cells and tissue specially when the tissue becomes…

Q: Trace in a stepwise manner the signaling pathway that involves a g-protein receptor leading to the…

A: Hormones are specific messenger that act through cell signalling after binding with specific…

Q: Which type of cancer has been treated with ipilumumab?With what success?

A: The immune system of the body protects the individual from the attack of external pathogens. The…

Q: targeted receptor over time.  True  False Cytokines are peptides that are generally made in…

A: A non-competitive antagonist is an insurmountable antagonist that can function in one of two ways:…

Q: Explain the structure and location of the cellular receptor and describe in detail the mechanism of…

A: Hormones are the chemical messengers which are secreted from the endocrine glands and through blood…

Q: Which choice properly identifies how racemic epinephrine is prepared?

A: Epinephrine is also known by the term adrenalin used to treat serious health issues like…

Q: In studies trying to understand the regulation of hormone-sensitive adenylate cyclase, it was…

A: Understanding the intricate regulation of hormone-sensitive adenylate cyclase is pivotal in…

Q: Describe the relationship between Insulin Growth Factor (IGF) and aging.  What role does IGF play in…

A: Insulin Growth Factor IGF is also called somatomedin C. It is structurally similar to the hormone…

Q: Describe the main mechanisms by which G proteins are activated upon norepinephrine binding

A: G proteins are molecular switches that are active when bound to GTP and capable of hydrolyzing the…

Q: Answer each question in about one sentence. (a) What is the biochemical basis for the action of…

A: (a) Viagra has the ability to prolong the effects of nitric oxide by inhibiting cyclic GMP…

Q: Explain in detail the funcations and signalling of ephrin receptors.  Provide examples.

A: Eph receptors are a class of receptors that are activated in response to interaction with Eph…

Q: a) Create a diagram which illustrates the typical signalling mechanism of action of each of the four…

A: Introduction :-  Receptors are the protein molecules inside the target cell or on its surface that…

Q: ive some abnormal conditions wherein the APTT is prolonged. Why is APTT employed in monitoring a…

A: Activated partial thromboplastin time are the test which is used for testing the  .In APTT , an…

Q: In the intact salivary gland, the major stimulus for secretion is input from the para sympathic (PS)…

A: The cellular response to a particular extracellular signal molecule depends on its binding to a…

Q: 1a.Arrange these ligands in their order of potencies(high to low) 1b. Choose an appropriate…

A: Receptors are membrane proteins consisting of proteins, and glycans. Its extracellular domain…

Q: Discuss how diabetic ketoacidosis (DKA) occurs and its clinical manifestations. In your response be…

A: A potentially fatal consequence of type 1 diabetes, diabetic ketoacidosis (DKA) may also, in certain…

Q: Which statement correctly identifies how a lipid-soluble hormone that diffuses from the blood and…

A: Lipid-soluble hormones are a class of hormones that are able to pass through cell membranes due to…

Q: Explain how mutations in the following proteins might result in either loss of responsiveness to a…

A: A mutation refers to the alteration in the nucleotide sequence of DNA. It is caused by physical,…