A protein called trypsin, which plays a role in digestion, is made bypancreatic cells and secreted from those cells. Starting with a sampleof pancreatic cells, a researcher modified the gene that encodes trypsin by mutating the ER signal sequence so it was no longer recognized by SRP. How would this mutation affect the targeting of trypsin?

Q: Describe the steps involved in the Direct Gene activation system. Give an example of a hormone that…

A: Steroid and thyroid hormones can diffuse through the lipid bilayer of the cell membrane and use the…

Q: You are given 3 tubes of RNA and asked by your supervisor to clone the gene encoding the proinsulin…

A: 1) Pancreatic islets consist of three types of cells namely, α-cells, β-cells, and δ-cells. The…

Q: 12445 RD-Hom 4(167-277) A(194-277) A(97-138) A(97-167) 6 A(97-194) N595A 7890 A(619-723) HD 10…

A: A regulatory protein regulates the expression of a gene by binding with that gene through its DNA…

Q: In an experiment performed in C. elegans three forms of RNA (sense RNA, antisense RNA, and…

A: The blocked gene expression would be observed more in doubled stranded RNA as compared to sense RNA…

Q: Suppose you discover a drug that has potential antiviral effect against SARS-CoV2 so you tested its…

A: In microarray, the cDNA of both treated and untreated cells well put together in a well for a…

Q: Please explain the role of the SRP, SRP receptor and the protein translocator in the synthesis of a…

A: After the proteins has been translated, it needs to be send to different areas in the cells to carry…

Q: Cancers are often caused by overactive growth factor receptor signaling (remember growth factor…

A: Cancer is a disease which is caused by the uncontrolled growth of the cells, without regulation of…

Q: What statement is FALSE regarding the molecule ppGpp? 1.This molecule is a bacterial second…

A: ppGpp is a molecule in which a nucleotide is attached to three additional phosphates as well. ppGpp…

Q: If a mutation is introduced into I-KBα that inhibits it phosphorylation by the IKK complex, this…

A: Mutation in I-KBα that inhibits its phosphorylation by the IKK complex can prevent the translocation…

Q: Given that the the trp operon is a negative repressible operon what happens to the trp repressor in…

A: Introduction  The lac operon model is a classic example of gene regulation in prokaryotic cells. The…

Q: Quorum sensing controls the expression of virulencein many pathogenic bacteria. Usually, pathogens…

A: Quorum sensing is a type of signaling that works between bacteria present in a region. Bacteria…

Q: Which of the following statements is not true of both the LacI and TrpR repressor proteins?a) an…

A: The objective of the question is to identify the statement that is not true for both LacI and TrpR…

Q: Briefly describe the following properties of the Ras GTPases: a) Size, structure and cellular…

A: a) Mature ras protein are located on the inner side of the plasma membrane, and their biochemical…

Q: Explain why mutations in the lacI gene are trans in their effects, but mutations in the lacO gene…

A: Lac operon is defined as an operon which is required for the metabolism and transport of a lactose…

Q: Which answer correctly shows a signal transduction pathway? GPCR -> Active Gq -> Active…

A: Please follow step 2 for detailed explanation.

Q: Referring to Figure 18.5, predict what would happen if the SRPRNA was unable to stimulate the GTPase…

A: Its primary objective is to locate SRP units. SRP (signal recognition particle) is a molecule that…

Q: You are given 3 tubes of RNA and asked by your supervisor to clone the gene encoding the proinsulin…

A: Restriction enzymes are use to cut DNA at specific sites, known as restriction sites. The…

Q: What would happen if the retinoblastoma protein wasn't able to bind to the E2F transcription factor?

A: The retinoblastoma protein (pRb) is a tumor suppressor protein that helps to prevent excessive cell…

Q: most cancer mutations in the ras/mapk pathway occur upstream of mapk rather than in mapk itself.

A: Cancer Cancer is defined as abnormal and uncontrolled cell proliferation in the body tissues.…

Q: The protein NK2 is a transcriptional regulator that functions both as a repressor and activator. To…

A: A regulatory protein regulates the expression of a gene by binding with that gene through its DNA…

Q: Why is phospholipase c is the target on this western blot explain in detail

A: Phospholipase C (PLC) is an enzyme that cleaves the phospholipids just before the attachment of…

Q: You are studying a patient with familial hypercholesterolemia. After performing a biopsy to obtain…

A: The LDL (known as bad cholesterol) is composed of lipoprotein, phospholipid cholesterol and some…

Q: The activity provides you with a version of the NGF pathway, an example of a RTK. All of the…

A: The given diagram showing Ras - MAP kinase pathway :-

Q: Draw a schematic diagram showing the components involved in the regulation of the tryptophan operon.

A: The trp operon is regulated by the trp repressor. When bound to tryptophan, the trp repressor blocks…

Q: The bacteria E Coli uses the Trp operon to control its production of tryptophan-producing enzymes.…

A: There are five structural genes in the tryptophan Operon along with the operator and the promoter…

Q: The DNA sequence before the protein coding region that determines when a gene is used is called the…

A: DNA is the genetic material of many organisms including the humans. The DNA contains information…

Q: While studying the secretory pathway, you make the following observation about proteins destined for…

A: 2-Dimensional polyacrylamide gel electrophoresis (2D-PAGE) is a technique through which proteins can…

Q: Based on the data provided, explain how cellular processes must be altered in stomach cancer cells…

A: In comparison to healthy cells, cancer cells have an active metabolism and need more energy. Cancer…

Q: Wilms tumor 1, or nephroblastoma, is caused by mutations in the WT1 gene, which encodes a…

A: Molecular biology is an emerging field which focuses on the molecular basis of all biological…

Q: Propose some possible reasons why mutations in the RPSA gene affect only the spleen and not other…

A: Spleen is a small part present in the gastro intestinal tract of an individual. Spleen has some…

Q: You are given 3 tubes of RNA and asked by your supervisor to clone the gene encoding the proinsulin…

A: The expression level of any expression vector depends on the regulatory elements like enhancer and…

Q: a) What you can expect for gene α regulation by this ligand? What signaling mechanism could be used?…

A: Cell signal involves three major steps- 1) binding of extracellular signaling molecules (ligands) to…

Q: Explain how Tryptophan acts as an effector?

A: To explain:  how Tryptophan acts as an effector

Immunology

Immunology is the division of science involved with the immune reactions occurring in living organisms. The organisms are accustomed to evolving internal defense mechanisms to evade the invasion of microbial pathogens. Diverse cells are connected with stimulating the immune responses, which produce inhospitable conditions to the microbes prompting their lysis and thus inhibits the multiplication of the pathogens. The immune system can distinguish the pathogens through the aid of cellular intercommunication and launch responses to destroy them.