What would happen if the retinoblastoma protein wasn't able to bind to the E2F transcription factor?

Q: Cells, including immune cells, degrade mRNA molecules in which no long open reading frame is…

A: An immune cell is a cell that is part of the body's immune system and will help the body fight…

Q: Describe the steps involved in the Direct Gene activation system. Give an example of a hormone that…

A: Steroid and thyroid hormones can diffuse through the lipid bilayer of the cell membrane and use the…

Q: Suppose you discover a drug that has potential antiviral effect against SARS-CoV2 so you tested its…

A: In microarray, the cDNA of both treated and untreated cells well put together in a well for a…

Q: The GA(T>C)A mutation in the Duffy promoter impacted expression of Duffy in the following cell…

A: The promoter is the region where the RNA polymerase binds during the transcription i.e. synthesis of…

Q: Which of the following would most likely mimic Rb loss? Rb mutant where the phosphosites are mutated…

A: Rb is a tumor suppressor gene. Loss of function mutation in Rb gene leads to the retinoblastoma and…

Q: seems that the expert only addressed the background of prorooncogen and the impact of Ras causing…

A: Protooncogenes are the genes that form the proteins that are responsible for cell division and cell…

Q: Describe Duchenne muscular dystrophy (DMD) including its cause and symptoms. Then, explain why DMD…

A: Myotonic dystrophy is a type of muscular dystrophy that affects the muscles as well as other body…

Q: If some cell-surface receptors, including Notch, can rapidly signal to the nucleus by activating…

A: The biological cells are a hub of metabolic activities. These cells interact among themselves to…

Q: If tryptophan is in high levels, will transcripition stop or initiate?

A: Transcription is a process in which a particular segment of DNA is copied into RNA by the enzyme RNA…

Q: Explain why in cells that are genetically NF1–/–, basal levels of GTP-bound activated Ras are higher…

A: Neurofibromatosis type 1 (NF1) is a typical hereditary problem portrayed by various neurofibromas,…

Q: List five proteins that interact with the CFTR protein.

A: Proteins that interact with CFTR protein.

Q: How gene expression is regulated by Ras mediated MAPK pathway?

A: If all the genes in a cell would be expressed, then the protein would accumulate in the cell and the…

Q: A researcher discovered Suramin as a potent and selective inhibitor of Mycobacterium tuberculosis…

A: Surarnin is a potent and selective inhibitor of the RecA protein in Mycobacterium tuberculosis (Mtb)…

Q: Do you think it would be easier to mutate the GR receptor or treat someone with a miRNA to overcome…

A: MicroRNAs are a grade of non-coding RNAs which plays vital role in managing gene expression. Large…

Q: What type of control generally involves binding of a repressor protein to a regulatory DNA sequence?…

A: Repressor : DNA binding protein which inhibits the expression of 1 or more genes via the binding to…

Q: Please explain in detail why is BCL-2 a suppressor of apoptosis

A: Bcl-2: a. It is the first apoptotic gene to be cloned and isolated from human follicular lymphomas.…

Q: in a fat cell what is the result of activation of genes by PPAR gamma/activator proteins binding?…

A: Peroxisome proliferator - activated receptor(PPAR) gamma is a  nuclear receptor of subfamily 1,group…

Q: List the Pol II general transcription factors.

A: Transcription factors is a protein that controls the rate of transcription of gentic information…

Q: MSH2 is a gene commonly associated with HNPCC (Hereditary nonpolyposis colorectal cancer). This gene…

A: Hereditary nonpolyposis colorectal cancer (HNPCC), also known as Lynch syndrome, is an inherited…

Q: What is the first step in growth factor pathway activation?

A: Growth factor work together with receptor and signalling pathway.  it play a crucial role in growth…

Q: What structural class of exteroreceptors is a slowly adapting mechanoreceptor for light pressure?

A: Mechanoreceptors detect stimuli such as touch, pressure, vibration, and sound from the external and…

Q: Describe and give an example of each of the following levels of gene expression control in…

A: Genes are a set of nucleotides sequence that carries information to be passed on from one generation…

Q: Question 22 Single stranded binding proteins assist transcription True False Question 23 A…

A: Transcription:Transcription is the synthesis of mRNA in 5' -> 3' direction from the template…

Q: A mutation in the repressor LacI causes it to lose the ability to bind its effector, allolactose.…

A: The question is asking about the effect of a mutation in the LacI repressor that causes it to lose…

Q: If tryptophan is in high levels, will transcripition stop or initiate?

A: DNA maintains genetic material in the nucleus of cells as in the usual term that state to define as…

Q: A which is involved in the silencing of the y-globin gene, is rendered inactive. CL11A is a Land a…

A: Gene silencing is a negative feedback process that controls gene expression and metabolism…

Q: How is the signal generated by binding of TGF-β to cell-surface receptors transmitted to the…

A: TGF-β is a cytokine of the transforming growth factor family of signaling molecules with multiple…

Q: The transcription factor Pax6 is required continually during the life of a mouse (or a human) for…

A: Pax6 is a kind of transcription factor which is required for the development of retina in mouse and…

Q: the visual system, it is critical to keep a subset of neuronal genes in a repressed state to…

A: HAT play an important role  in regulations of gene expression. it helps to increase gene…

Q: Explain how the Pyrococcus furiosus TrmBL1 transcriptionregulator is able to act as both an…

A: An activator is a regulator Pyrococcus furiosus substance that enhances the gene expression whereas…

Q: hey hyper-activity of a protein? can cause

A: Proto-oncogene : These are normal genes that helps cells to grow. An oncogene is any gene that can…

Q: A normal cell has no growth factor bound to the growth factor receptor. What do you predict about…

A: The extracellular signal-regulated kinase (ERK) pathway is an important pathway that cells use to…

Q: How does each of these small GTP-binding proteins contribute to the regulation of cell migration?

A: GTP bonding protein also known as G protein.G protein is present in eukaryotic and classifieds into…

Q: What is the effect of an increased Cro concentration on the expression of the gene for the λ…

A: The lytic cycle is the rupture of the host cell, resulting in the release of a number of viruses.…

Q: Some transcription factors contain bromodomains. Explain the function of the bromodomain?

A: Transcription factors are responsible for intiating the transcription process. The transcript…

Q: What are the functions of transcriptional activator proteins and repressor proteins? Explain how…

A: Transcription is the first step in central dogma of protein synthesis. It involves formation of…

Q: Which molecules act as co-repressor for pur respressor in prokaryotes?

A: Co repressor- It's a substance which inhibits the gene expression.A co repressor downregulates the…

Q: Which promoter initiates which life cycle (lysogenic & Lytic)? Mention both types of promoters and…

A: Viruses reproduce by utilising a host cell to produce additional viruses, which subsequently burst…

Q: How could the increase in a protein that inhibits the activity of sigma-32 lead to an increase in…

A: The "molecular chaperone", dnaK, is induced upon heat shock and promotes ATP-dependent refolding or…

Q: Which kind of therapy was given in 1990 to a four year old girl with adenosine deaminase (ADA)…

A: Answer: Introduction: ADA deficiency i.e. Adenosine deaminase deficiency is also called as severe…

Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.