A polydactylous, normal-visioned, brown-eyed man with wavy hair has a nonpolydactylous, blue-eyed mother. He proposed marriage to a nonpolydactylous, astigmatic, blue-eyed, and curly-haired lady whose mother has normal vision. However, the lady is worried about the proposal since sickle-cell anemia has been known to run in both their families. Is there a genetic basis for her worry? Explain.
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A polydactylous, normal-visioned, brown-eyed man with wavy hair has a nonpolydactylous, blue-eyed mother. He proposed marriage to a nonpolydactylous, astigmatic, blue-eyed, and curly-haired lady whose mother has normal vision. However, the lady is worried about the proposal since sickle-cell anemia has been known to run in both their families.
Is there a genetic basis for her worry? Explain.
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- The mother of a family with 10 children has blood typeRh+. She also has a very rare condition (elliptocytosis,phenotype E) that causes red blood cells to be oval rather than round in shape but that produces no adverseclinical effects. The father is Rh− (lacks the Rh+ antigen)and has normal red blood cells (phenotype e). The children are 1 Rh+ e, 4 Rh+ E, and 5 Rh− e. Information isavailable on the mother’s parents, who are Rh+ E andRh− e. One of the 10 children (who is Rh+ E) marriessomeone who is Rh+ e, and they have an Rh+ E child.a. Draw the pedigree of this whole family.b. Is the pedigree in agreement with the hypothesisthat the Rh+ allele is dominant and Rh− is recessive?c. What is the mechanism of transmission ofelliptocytosis?d. Could the genes governing the E and Rh phenotypesbe on the same chromosome? If so, estimate the mapdistance between them, and comment on your resultA polydactylous, normal-visioned, brown-eyed man with wavy hair has a nonpolydactylous, blue-eyed mother. He proposed marriage to a nonpolydactylous, astigmatic, blue-eyed, and curly-haired lady whose mother has normal vision. However, the lady is worried about the proposal since sickle-cell anemia has been known to run in both their families. If it turned out that the lady is a carrier and the man has normal RBC, what would be their COMPLETE genotypes? Based on their genotypes, what is the probability that they would have: 1. nonpolydactylous child with normal vision? 2. polydactylous, astigmatic child and sickle-trait carrier? 3. a boy with his father’s genotype? 4. a girl with her mother’s genotype?A polydactylous, normal-visioned, brown-eyed man with wavy hair has a nonpolydactylous, blue-eyed mother. He proposed marriage to a nonpolydactylous, astigmatic, blue-eyed, and curly-haired lady whose mother has normal vision. However, the lady is worried about the proposal since sickle-cell anemia has been known to run in both their families. a. Is there a genetic basis for her worry? Explain. b. If it turned out that the lady is a carrier and the man has normal RBC, what would be their COMPLETE genotypes? Male genotype:Female genotype: c. Based on their genotypes, what is the probability that they would have: c.1 a child homozygous for normal RBC? c.2 nonpolydactylous child with normal vision? c.3 polydactylous, astigmatic child and sickle-trait carrier? c.4 a boy with his father’s genotype? c.5 a girl with her mother’s genotype?
- Another couple is concerned their child will be born with sickle cell anemia. The woman does not have sickle cell anemia. The woman’s mother had sickle cell anemia and her father was a carrier of the sickle cell gene. The man knows that he is not a carrier of the sickle cell gene. What is the probability that the child will be a carrier of sickle cell anemia?Another couple is concerned their child will be born with sickle cell anemia. The woman does not have sickle cell anemia. The woman’s mother had sickle cell anemia and her father was a carrier of the sickle cell gene. The man knows that he is not a carrier of the sickle cell gene. What is the probability that the child will be a carrier of sickle cell anemia? please include a punnett squareA phenotypically normal man, who has a hemophiliac brother, marries a normal woman, who is not a carrier. What is the probability that any of their children will be hemophiliac?
- O. 2 Hemophilia A is an X-linked trait where blood clotting is affected due to a mutation in a clotting factor protein. Georgio has hemophilia and attends a support group where he meets Gbenga, who does not have the disease, but whose father has hemophilia. Her mother is not affected. A) If they marry, what percentage % of all their children will have hemophilia? % B) Georgio meets another woman, Maria, at the hemophilia support group. Maria also lacks the trait, but her mother has hemophilia while her father is unaffected. # 3 Would a Georgio-Maria mating provide a larger chance of having afflicted children compared to a Georgio-Gbenga mating? C) Show how you came up with your answer to B. Edit View Insert Format Tools Table 12pt ✓ 80 F3 V Paragraph ✓ $ 4 Yes or No 000 000 F4 DO LO % 5 BIUAV T² | F5 ^ MacBook Air 6 2 F6 V & 7 F7 * 8 DII F8 ( 9 DD F9 1 0 S FA man with thalassemia minor marries a normal woman. What phenotypic ratios of thalassemia-affected children might these parents expect?Hemophilia is an X-linked disease associated with the inability to produce specific proteins in the blood-clotting pathway. Shown above is a family pedigree tree in which family members afflicted with the disease are shown with filled-in squares (male) or circles (females). A couple is trying to determine the likelihood of passing on the disease to their future children (represented by the ? symbol above) because the hemophilia runs in the woman’s family 4.Assuming that the woman in the couple is a carrier, what is the probability that the couple’s first son will have hemophilia?
- Suppose a woman who is a carrier of sickle-cell trait (making her a heterozygote) has children with a man who is totally healthy and does not carry the gene for sickle-cell trait at all. Which one of the following is true about their potential children? (Draw a Punnett square on scratch paper if it helps you.) A) None of their children will have sickle-cell disease. B) All of their children will have sickle-cell disease. C) All of the couple's children would be heterozygous carriers like the mother.I will be adding two questions here because I asked two of the same questions twice by accident earlier. A man and a woman do not have hemophilioa, but the womans father did. (Hemophilia is X-linked recessive). a) What is the probability that they will have a child with hemophilia? b) Is it possible for any of their daughters to be affected? Explain. A cross between a horse homozygous for red hair and a horse homozygous for white hair results in offspring with the coat colour called roan. When you look at the fur of the roan offspring you see both red and white hairs. What type of inheritance best explains this? a) blending inheritance b)codominance c)incomplete codominance d)multiple allelesAlpha thalassemia is a hereditary blood condition that results in varying levels of anemia. It is tied to the HB alpha 1 gene and the HB alpha 2 gene on human chromosome 16. The diagram shows the proteins for the hemoglobin genes and the pedigree shows genotypes, designated by the letter X, on the chromosomes for a family affected by the condition. Which represents the predicted level of anemia in a child born to the mother and father in the image with a mutation that results in a genotype of xxxx? Why? A - mild anemia because the loss of 4 genes would equal the loss of the 4 proteins needed for normal alpha hemoglobin B - severe anemia because the loss of 4 genes would equal the loss of the 4 proteins needed for normal alpha hemoglobin C - mild anemia because the addition of 4 genes would produce too many of the proteins needed for normal alpha hemoglobin D - severe anemia because the addition of 4 genes would produce too many of the proteins needed for normal alpha hemoglobin