Sickle cell anemia is an inheritable red blood cell disorder that results in sickle-shaped red blood cells. The sickle-shaped red blood cells can stick to blood vessel walls and cause a blockage or slow the movement of blood throughout the body. Individuals who are heterozygous produce both normal and sickle-shaped red blood cells which gives them resistance to malaria but they do not develop sickle cell anemia (so heterozygotes are unaffected on the pedigree). Let HbS be the allele for sickle cell anemia and let HbA be the allele for normal red blood cells. Which of the following rows provides the correct genotypes for individuals I-2, I-4, II-1, and III-1? Select one: a. I-2 I-4 II-1 III-1 HbA_ HbAHbS HbAHbS HbA_ b. I-2 I-4 II-1 III-1 HbA_ HbAHbS HbAHbS HbAHbS c. I-2 I-4 II-1 III-1 HbAHbS HbAHbS HbAHbS HbAHbS d. I-2 I-4 II-1 III-1 HbAHbA HbAHbA HbAHbA HbAHbA
Sickle cell anemia is an inheritable red blood cell disorder that results in sickle-shaped red blood cells. The sickle-shaped red blood cells can stick to blood vessel walls and cause a blockage or slow the movement of blood throughout the body. Individuals who are heterozygous produce both normal and sickle-shaped red blood cells which gives them resistance to malaria but they do not develop sickle cell anemia (so heterozygotes are unaffected on the pedigree). Let HbS be the allele for sickle cell anemia and let HbA be the allele for normal red blood cells. Which of the following rows provides the correct genotypes for individuals I-2, I-4, II-1, and III-1? Select one: a. I-2 I-4 II-1 III-1 HbA_ HbAHbS HbAHbS HbA_ b. I-2 I-4 II-1 III-1 HbA_ HbAHbS HbAHbS HbAHbS c. I-2 I-4 II-1 III-1 HbAHbS HbAHbS HbAHbS HbAHbS d. I-2 I-4 II-1 III-1 HbAHbA HbAHbA HbAHbA HbAHbA
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Sickle cell anemia is an inheritable red blood cell disorder that results in sickle-shaped red blood cells. The sickle-shaped red blood cells can stick to blood vessel walls and cause a blockage or slow the movement of blood throughout the body. Individuals who are heterozygous produce both normal and sickle-shaped red blood cells which gives them resistance to malaria but they do not develop sickle cell anemia (so heterozygotes are unaffected on the pedigree).
Let HbS be the allele for sickle cell anemia and let HbA be the allele for normal red blood cells.
Which of the following rows provides the correct genotypes for individuals I-2, I-4, II-1, and III-1?
Select one:
a.
| I-2 | I-4 | II-1 | III-1 |
|---|---|---|---|
| HbA_ | HbAHbS | HbAHbS | HbA_ |
b.
| I-2 | I-4 | II-1 | III-1 |
|---|---|---|---|
| HbA_ | HbAHbS | HbAHbS | HbAHbS |
c.
| I-2 | I-4 | II-1 | III-1 |
|---|---|---|---|
| HbAHbS | HbAHbS | HbAHbS | HbAHbS |
d.
| I-2 | I-4 | II-1 | III-1 |
|---|---|---|---|
| HbAHbA | HbAHbA | HbAHbA | HbAHbA |
Transcribed Image Text:Pedigree Conventions
Identical
twins
Male
Female
Non-identical
twins
Mating
Affected
individuals
Mating between
close relatives
Unaffected
individuals
Roman numerals
symbolize generations
Arabic numbers
II ON
symbolize individuals
within a given
generation
1
2 3
Birth order, within each
group of offspring, is
drawn left to right,
oldest to youngest
Transcribed Image Text:Generation
1
3
4
II
II
1 2
2.
ON
2.
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