Sickle cell anemia is an inheritable red blood cell disorder that results in sickle-shaped red blood cells. The sickle-shaped red blood cells can stick to blood vessel walls and cause a blockage or slow the movement of blood throughout the body.   Individuals who are heterozygous produce both normal and sickle-shaped red blood cells which gives them resistance to malaria but they do not develop sickle cell anemia (so heterozygotes are unaffected on the pedigree). Let HbS be the allele for sickle cell anemia and let HbA be the allele for normal red blood cells. Which of the following rows provides the correct genotypes for individuals I-2, I-4, II-1, and III-1? Select one: a. I-2 I-4 II-1 III-1 HbA_ HbAHbS HbAHbS HbA_ b. I-2 I-4 II-1 III-1 HbA_  HbAHbS HbAHbS HbAHbS c. I-2 I-4 II-1 III-1 HbAHbS HbAHbS HbAHbS HbAHbS d. I-2 I-4 II-1 III-1 HbAHbA HbAHbA HbAHbA HbAHbA

If a person has albinism and dark skinned parents what is their genotype

what fraction of the offspring of two parents with sickle trait would you expect to have sickle cell anemia? Explain how you arrived at this answer. Also include a punnet square

A man with type AB blood has a child with a woman who has type O blood. Which of the following correctly represents the probability of the child’s blood type(s)? a) 25% type A, 50% type AB, 25% type B b) 100% type O c) 50% type AB, 50% type O d) 50% type A, 50% type B e)100% type O

Given the information regarding sickle cell anemia, if two carriers were to have children, what would be the genotypes and phenotypes of their children? Would any of the children show symptoms of the disease?

Barbara and John have two daughters (Madison and Kelly), and one son (Mike), all have normal red blood cells. Their other son (Chase) has been diagnosed with sickle cell. Barbara recently gave birth to another son (Barry) who also has been diagnosed with sickle cell. Barbara’s mother (Beth) has sickle cell, but her father (Jason), three sisters (Emma, Lori, and Allison), and two brothers (Emmitt and Will) are all normal. John’s father (Jim), mother (Brenda), and brother (Parker) are all normal, but his sister (Demi) has sickle cell. John’s maternal grandparents (Bill and Lonna) are carriers. Barbara’s paternal grandparents (Kevin and Martha) are all normal      Paternal = a person’s dad’s side of the family Maternal = a person’s mom’s side of the family 1. Draw a pedigree to show how this trait could affect this family within each generation 2. Shade all individuals affected with the disorder. Half shade all carriers. 3. Assign genotypes to every individual. Use Punnett squares to…

Sickle Cell Anemia is caused by an abnormal form of haemoglobin, the part of the red blood cell that carries oxygen around the body. The red blood cells become stiff and block blood vessels, causing pain and damage and quickly destroying blood cells, leading to anemia.     It is estimated that approximately 1 in 32 000 people in Canada are affected with sickle cell anemia.The disorder occurs when a person inherits two recessive genes for the condition. What are the frequencies of the recessive disease allele and the dominant normal allele in the population's gene pool? Select one: a. Recessive Allele Dominant Allele 0.559% 99.4% b. Recessive Allele Dominant Allele 5.59% 94.4% c. Recessive Allele Dominant Allele 0.313% 99.7% d. Recessive Allele Dominant Allele 0.00313% 99.9%

What would happen to the frequency of heterozygous carriers of sickle-cell anemia (with AS genotype) if mosquitoes were completely wiped out in a large region?

ABO blood groups, an autosomal trait, in Humans are genetically determined. A woman with type O blood has a son with type O. What are the possible genotype(s) of the son, his mother and possible father?                 Mother:                Father:                 Son:

a) What are all the possible genotypes of an individual with type A blood? (We are not considering Rh factor for these problems)   b) Marge has type B blood and Homer has type A. What are all the possible blood types that their kids could have?   c) Nikki has type AB blood. She is in a car accident and is critically injured. The hospital is out of all blood except type O. Can Nikki have a transfusion of type O blood? Explain your answer.