A newly described rare and potentially fatal condition causes heart rate to be unusually low in adults (between 30-45 beats per minute). A series of studies have shown a possible genetic link. Normal heart rate in adults is typically between 60 to 100 bpm. A family's medical chart that includes afflicted individuals is provided below. As a medical researcher, your supervisor asks you to produce a pedigree of this family to visualize and to determine a possible pattern of inheritance for this condition. As such, based on the data, draw the pedigree (clearly identifying who is afflicted and not afflicted) and your conclusion as to the mode of inheritance of this condition. Explain your reasoning.

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter4: Pedigree Analysis In Human Genetics
Section: Chapter Questions
Problem 10QP: A proband female with an unidentified disease seeks the advice of a genetic counselor before...
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A newly described rare and potentially fatal condition causes heart rate to be unusually low in adults
(between 30-45 beats per minute). A series of studies have shown a possible genetic link. Normal heart rate
in adults is typically between 60 to 100 bpm. A family's medical chart that includes afflicted individuals is
provided below. As a medical researcher, your supervisor asks you to produce a pedigree of this family to
visualize and to determine a possible pattern of inheritance for this condition.
As such, based on the data, draw the pedigree (clearly identifying who is afflicted and not afflicted) and
your conclusion as to the mode of inheritance of this condition. Explain your reasoning.
Name
Relation
age
ВРМ
Claire
Grandparent; James'
spouse
85yrs
99 bpm
45 bpm
41bpm
68bpm
40bpm
85bpm
86bpm
90bpm
Grandparent; Claire’s spouse
son to Claire and James; Indra’s spouse
son to Claire and James; Mary’s spouse
87yrs
55уrs
53 yrs
49уrs
55уrs
54yrs
49уrs
James
Ricky
Jimmy
daughter to Claire and James; Olivier's
Ricky's partner
Jimmy's spouse
Lilith's spouse
Lilith
spouse
Indra
Mary
Olivier
Robbie
Travis
Siblings
Daughter to Ricky and Indra
Son to Ricky and Indra
35yrs
25уrs
33 yrs
38bpm
70bpm
90bpm
Tristan
Son to Jimmy and Mary
Eliane
Jean
Siblings
Daughter to Lilith and Olivier
Son to Lilith and Olivier
16уrs
14yrs
10уrs
89bpm
43bpm
37bpm
Luc
Son to Lilith and Olivier
Transcribed Image Text:A newly described rare and potentially fatal condition causes heart rate to be unusually low in adults (between 30-45 beats per minute). A series of studies have shown a possible genetic link. Normal heart rate in adults is typically between 60 to 100 bpm. A family's medical chart that includes afflicted individuals is provided below. As a medical researcher, your supervisor asks you to produce a pedigree of this family to visualize and to determine a possible pattern of inheritance for this condition. As such, based on the data, draw the pedigree (clearly identifying who is afflicted and not afflicted) and your conclusion as to the mode of inheritance of this condition. Explain your reasoning. Name Relation age ВРМ Claire Grandparent; James' spouse 85yrs 99 bpm 45 bpm 41bpm 68bpm 40bpm 85bpm 86bpm 90bpm Grandparent; Claire’s spouse son to Claire and James; Indra’s spouse son to Claire and James; Mary’s spouse 87yrs 55уrs 53 yrs 49уrs 55уrs 54yrs 49уrs James Ricky Jimmy daughter to Claire and James; Olivier's Ricky's partner Jimmy's spouse Lilith's spouse Lilith spouse Indra Mary Olivier Robbie Travis Siblings Daughter to Ricky and Indra Son to Ricky and Indra 35yrs 25уrs 33 yrs 38bpm 70bpm 90bpm Tristan Son to Jimmy and Mary Eliane Jean Siblings Daughter to Lilith and Olivier Son to Lilith and Olivier 16уrs 14yrs 10уrs 89bpm 43bpm 37bpm Luc Son to Lilith and Olivier
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