A 42 year old female visits her GP. She complains of stiffness and occasional uncontrolled movement in her arms. On occasions, and especially in the evenings, she found it difficult to eat and drink. < 1. What is the most likely diagnosis, based on these symptoms, and why? (suggest <30 words).< 2. Describe the molecular pathogenesis of this disorder, i.e. at the molecular and cellular level, how does this disease state emerge (suggest <150 words)?< له ( لے The GP initially prescribes a low dose of L-DOPA along with carbidopa.< 3. Describe the mode of action of L-DOPA (suggest <100 words).< لے

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Chapter11: Endocrine System
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A 42 year old female visits her GP. She complains of stiffness and occasional uncontrolled movement
in her arms. On occasions, and especially in the evenings, she found it difficult to eat and drink. <
له
1. What is the most likely diagnosis, based on these symptoms, and why? (suggest <30 words).<
(
The GP initially prescribes a low dose of L-DOPA along with carbidopa.<
(
(
2. Describe the molecular pathogenesis of this disorder, i.e. at the molecular and cellular level,
how does this disease state emerge (suggest <150 words)?<
3. Describe the mode of action of L-DOPA (suggest <100 words).<
4. What is the function of carbidopa, and how does it work (suggest <100 words)?<
The patient returns 3 months later. While the rigidity and tremors have slightly improved, they are
still causing problems. In the meantime, the patient says she has been feeling down for a while, is
having suicidal thoughts and is finding it difficult to sleep.<
(
(
5. How would you treat this patient now? If you decide to prescribe any new drugs, describe
their mode of action (suggest <200 words).<
Transcribed Image Text:A 42 year old female visits her GP. She complains of stiffness and occasional uncontrolled movement in her arms. On occasions, and especially in the evenings, she found it difficult to eat and drink. < له 1. What is the most likely diagnosis, based on these symptoms, and why? (suggest <30 words).< ( The GP initially prescribes a low dose of L-DOPA along with carbidopa.< ( ( 2. Describe the molecular pathogenesis of this disorder, i.e. at the molecular and cellular level, how does this disease state emerge (suggest <150 words)?< 3. Describe the mode of action of L-DOPA (suggest <100 words).< 4. What is the function of carbidopa, and how does it work (suggest <100 words)?< The patient returns 3 months later. While the rigidity and tremors have slightly improved, they are still causing problems. In the meantime, the patient says she has been feeling down for a while, is having suicidal thoughts and is finding it difficult to sleep.< ( ( 5. How would you treat this patient now? If you decide to prescribe any new drugs, describe their mode of action (suggest <200 words).<
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