A 60-year-old male patient has been diagnosed with AD. His MMSE score is 15. The patient complained of inadequate sleep. Although he falls asleep quickly at night, he wakes up too early. He tried CBT-I for eight weeks without any noticeable improvement of the sleep disorder. The patient takes ketoconazole (a Cyp 3A inhibitor) for a fungal infection. He has chronic constipation and a history of drug abuse. Which drug(s) among suvorexant, zolpidem, and doxepin would be suitable for treating the sleep disorder of this patient? Explain. Please answer at your own easy words. Answer should be to the point (specific).
A 60-year-old male patient has been diagnosed with AD. His MMSE score is 15. The patient complained of inadequate sleep. Although he falls asleep quickly at night, he wakes up too early. He tried CBT-I for eight weeks without any noticeable improvement of the sleep disorder. The patient takes ketoconazole (a Cyp 3A inhibitor) for a fungal infection. He has chronic constipation and a history of drug abuse. Which drug(s) among suvorexant, zolpidem, and doxepin would be suitable for treating the sleep disorder of this patient? Explain. Please answer at your own easy words. Answer should be to the point (specific).
Chapter22: Pharmacology
Section: Chapter Questions
Problem I2CRE
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Question
A 60-year-old male patient has been diagnosed with AD. His MMSE score is 15. The patient
complained of inadequate sleep. Although he falls asleep quickly at night, he wakes up too early. He tried
CBT-I for eight weeks without any noticeable improvement of the sleep disorder. The patient takes
ketoconazole (a Cyp 3A inhibitor) for a fungal infection. He has chronic constipation and a history of
drug abuse.
Which drug(s) among suvorexant, zolpidem, and doxepin would be suitable for treating the sleep
disorder of this patient? Explain.
Please answer at your own easy words. Answer should be to the point (specific).
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