60. During a study of thyroid hormone function, an experimental line of mice is genetically engineered. The line of mice is tested for the synthesis, storage, and release of triiodothyronine (T) and thyroxine (T). Results show no abnormalities. However, the mice display findings consistent with hypothyroidism. The inability of these mice to respond to T, and T, is most likely caused by a defect in which of the following receptors? A) Cytokine receptor-linked kinase OB) G protein-coupled C) Nuclear DNA-bound D) Serine kinase E) Tyrosine kinase

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
icon
Related questions
Question
60. During a study of thyroid hormone function, an experimental line of mice is genetically engineered. The line of mice is tested for the synthesis, storage, and release of triiodothyronine (T3)
and thyroxine (T4). Results show no abnormalities. However, the mice display findings consistent with hypothyroidism. The inability of these mice to respond to T3 and T4 is most likely caused
by a defect in which of the following receptors?
A) Cytokine receptor-linked kinase
B) G protein-coupled
C) Nuclear DNA-bound
D) Serine kinase
E) Tyrosine kinase
Transcribed Image Text:60. During a study of thyroid hormone function, an experimental line of mice is genetically engineered. The line of mice is tested for the synthesis, storage, and release of triiodothyronine (T3) and thyroxine (T4). Results show no abnormalities. However, the mice display findings consistent with hypothyroidism. The inability of these mice to respond to T3 and T4 is most likely caused by a defect in which of the following receptors? A) Cytokine receptor-linked kinase B) G protein-coupled C) Nuclear DNA-bound D) Serine kinase E) Tyrosine kinase
Expert Solution
steps

Step by step

Solved in 2 steps

Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON