6. In an experiment, students used liver tissue samples to study the ethanol metabolism and the possibility of ethanol conversion into glucose. The ethanol introduction in the investigated medium didn't lead to glucose level increase. Why is it impossible to convert ethanol to glucose? For the answer: a) provide a scheme of gluconcogenesis, indicate the substrates of this process; b) write the reaction of ethanol oxidation in the liver; c) explain whether it is possible to use the metabolites of ethanol catabolism for the glucosc synthesis.

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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6. In an experiment, students used liver tissuc samples to study the cthanol
metabolism and the possibility of ethanol conversion into glucose. The ethanol
introduction in the investigated medium didn't lead to glucose level increase.
Why is it impossible to convert ethanol to glucose? For the answer:
a) provide a scheme of gluconcogenesis, indicate the substrates of this process;
b) write the reaction of ethanol oxidation in the liver;
c) explain whether it is possible to use the metabolites of ethanol catabolism for
the glucose synthesis.
Transcribed Image Text:6. In an experiment, students used liver tissuc samples to study the cthanol metabolism and the possibility of ethanol conversion into glucose. The ethanol introduction in the investigated medium didn't lead to glucose level increase. Why is it impossible to convert ethanol to glucose? For the answer: a) provide a scheme of gluconcogenesis, indicate the substrates of this process; b) write the reaction of ethanol oxidation in the liver; c) explain whether it is possible to use the metabolites of ethanol catabolism for the glucose synthesis.
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