Which statement best describes the reason why some of the reactions of glycolysis cannot be run in reverse in gluconeogenesis? The last reactions occur in mitochondria and reactions there can never be 1) reversed. 2) Glycolysis includes isomerization reactions and these can never be reversed. O 3) There are some allosteric enzymes and allosteric enzymes can never be reversed. 4) Some reactions have such large negative free energy changes that they can never be reversed under cellular conditions.
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- Identify the following as a characteristic of one or more following process: glycolysis, glycogenesis, Glycogenolysis, and gluconeogenesis. 1. Glucose 6-phosphate is the initial reactant 2. Glucose is the final product 3. Glucose 6-phosphate is produced in the first step 4. UTP is involved in the process 5. ADP is converted to ATP in this processc) As what molecule does each of the monosaccharides enter glycolysis? d) How many moles of ATP are generated from the complete oxidation of one mole of lactose? Show all the steps for the calculation of moles of ATP. Be sure to account for energy used in activating the components of lactose so that they can enter glycolysis.Glucose is converted to pyruvate in glycolysis, yielding a netsynthesis of 2 ATP. In certain cells pyruvate can be reconverted to glucose during gluconeogenesis. How many ATPsare required to convert pyruvate back to glucose?
- Draw OUT THE arrow pushing reaction mechanism for the following steps of glycolysis: SHOW/IDENTIFY the arrow pushing mechanism in at least 2 steps. CH,OPO CH,OH hexokinase 2+ H H H H H H ОН + ATP OH H ADP + H+ H ОН + НО HO OH H ОН H ОН Glucose-6-phosphate (G6P) GlucoseIndicate at what step in the glycolysis pathway each of the following events occur 1. First phosphorylation of ADP occurs 2. First “energy rich” compound is produced 3. Second “energy rich” compound undergoes reaction 4. First isomerization reaction occurs 5. Second formation of ATP occurs 6. Second “energy rich” compound is produced 7. ATP is converted to ADP for the second time 8. A dehydration reaction occursA figure of the energy payoff phase of glycolysis is shown below. Look at the reaction labelled with a 6 (on the far left), which involves the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate. reduced? HC O CHOH CH₂O-P Glycer- aldehyde 3-phosphate (G3P) 2 NADH 2 NAD+ + 2 H+ Triose phosphate 2 P₁ dehydrogenase Copyright © 2018 Pearson Canada Inc. P CHOH CH₂0-P 1,3-Bisphospho- glycerate 1,3- bisphosphoglycerate NADH NAD+ 2 ADP GLYCOLYSIS: Energy Payoff Phase Glyceraldehyde-3-phosphate 2 ATP Phospho- glycerokinase 2 Which of the compounds is C=O CHOH H–CO- P Phospho- CH₂0-P glyceromutase CH₂OH 8 3-Phospho- glycerate C=O 2-Phospho- glycerate 2. ATP 2 ADP BYD Pyruvate kinase 10 2 H₂O Enolase 2 C=O CO-P CH2 Phosphoenol- pyruvate (PEP) CH3 Pyruvate
- You have isolated a heterotrophic bacterium from the soil that has a mutation in the enzyme aldose, making it unable to produce glyceraldehyde 3-phosphate, or hydroxyacetone monophosphate. What consequences would this have on glycolysis? What other metabolic pathway could it use to produce energy? .Why? Explain the route you chose.Which of the following about glycolysis ARE/IS correct? (choose all that apply) a) During glycolysis, a Cys residue on an enzyme works as a nucleophile to attack a carbonyl group on a substrate. b) The net result of a single glycolysis run on one molecule of glucose creates two molecules of pyruvate and 2 ATP c) If you label C3 and C4 in glucose, after it is converted to lactate, you can't find any labeled carbons. please explain your answer(s)Glycolysis & Gluconeogenesis are both spontaneous. If both pathways were simultaneously active in a cell, it would constitute a "futile cycle" that would waste energy. Explain it.
- Match the following B vitamins with the roles of their coenzymes: riboflavin [ Choose ] niacin [ Choose ] pantothenic acid [ Choose ] vitamin B6 [ Choose ]Step 4 of the pentose phosphate pathway converts ribulose-5-phosphate to ribose-5-phosphate. Which glycolytic reaction does this reaction resemble and what type of enzyme catalyzes it?How many enyzymatic reactions are there in glycolysis pathway?