4. Different populations of mouse L-cells that lack cadherins were transfected with either E-cadherin or P-cadherin. If cells expressing E-cad are mixed with those expressing P-cad, theysegregate into distinct balls of cells (A in figure). However, if cells expressing different levels ofthe same cadherin are mixed, they form a single ball, with the high expressing cells in the centerB in the figure).(A)E-cadherinSORTINGOUTP-cadherin(B) low P-cadherinSORTINGOUThigh P-cadherinWhy do the cells expressing different levels of cadherin segregate as in (B) in the figure, andwhy not into two separate balls, or one ball with a different organization (randomly mixed, orhigh expressors on the outside)?

Cadherins are "calcium-dependent adhesion molecules" that are important in the formation of…

Answered: 4. Different populations of mouse…

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter15: From Dna To Protein

Section: Chapter Questions

Problem 8TYK

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