2.(a) List the number of NADH and FADH2 equivalents formed and the correspondingnumber of ATP equivalents generated by mitochondrial oxidation of one molecule ofCH3(CH2) 12-COSCOANumber of NADH orFADH₂ formedNumber of ATPultimately formedªEnzyme catalyzing the oxidation stepB OxidationAcyl-CoA dehydrogenaseB-Hydroxyacyl-CoA dehydrogenaseCitric acid cycleIsocitrate dehydrogenasea-ketoglutarate dehydrogenaseSuccinyl-CoA synthetaseSuccinate dehydrogenaseMalate dehydrogenaseTotalaThese calculations assume that mitochondrial oxidative phosphorylation produces 1.5 ATP per FADH2oxidized and 2.5 ATP per NADH oxidized.GTP produced directly in this step yields ATP in the reaction catalyzed by nucleoside diphosphate kinase(p. 516).

The fatty acid with 14 C is called myristic acid. Beta oxidation involves the sequential removal of…

Answered: 2. (a) List the number of NADH and…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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. FAD is a stronger oxidant than NAD*; FAD has a higher standard reduction potential than NAD*. Yet in the last reaction of the pyruvate dehydrogenase complex Explain this apparent paradox. FADH, bound to the Eg subunit is oxidized by NAD*.
In the section dealing with “NAD+ in disease” it is mentioned that metabolomics resultsindicate that impaired mitochondrial function contributes to some of the mentioneddiseases. Which metabolites can potentially accumulate when complex I of theelectron transport chain is defective? Use Fig 1 for guidance
Write the equation for net citric acid cycle and calculate one cycle equivalent to how many ATP?
Calculate the amount of ATPthat can be produced fromone molecule of 8:0 fatty acid metabolized aerobicallythrough ß-oxidation cycle and the citric acid cycle.
which statements are False?
Which of the following is higher during high levels of glutathione reductase and NADP? SH A но (GSH) OH NH2 NH2 HO OH ;-CH-CH2-CH2-C-NH-CH–ċ–NH–CH2- CH2 В (GSSG) CH2 -CH-CH;-CH2=C-NH–C NH-CH–Ç-NH-CH2-C HO OH NH2
9. The equation below depicts the first step of the citric acid cycle. H0 CoA-SH CH-C + 0=C-CO0 HO C-COO citrate s-COA ČH2-COO synthase ČH2 -CO0 Citrate Acetyl-CoA Oxaloacetate AG" = -32.2 kJ/mol a) Explain the chemical conversions that take place during this step. b) Why is this reaction energetically favorable? Explain.
Acetyi CoA Oxaloncetate CoA NADH NAD: Citrate Isccitrate Malate NAD co NADH Funaate »FADH; FAD a- Ketoglutarate Succinate NAD ATP Succinyt CuA NADH ADP - P, If you were told to add one of the eight citric acid cycle intermediates to the culture medium fo yeast growing in the laboratory, what do you think would happen to the rates of ATP and carbon dioxide production? (see the above figure) a. There would be no change in ATP production, but the rate of CO2 production would increase. b. The rates of ATP production and CO2 production would both increase, c. The rate of ATP production would increase, but the rate of CO2 production would decrease. d. The rates fo ATP and CO2 production would both decrease.
Help me understand this…I’m confused
. In deciding which form of isocitrate dehydrogenase plays the more important role in the citric acid cycle-the NAD*-dependent or the NADP*-dependent form-what kinds of information would help you?
L What is the difference between the type of oxidation catalyzed by acyl-CoA dehydrogenase and that catalyzed by b-hydroxyCoA dehydrogenase
if each nadh generates 3 atp molecules and each fadh2 generates 2 atp molecules calculate the number of ATP molecules generated from one saturated 10-carbon fatty acid

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