Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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. Briefly describe the biological rationale for cach of the following allosteric
phenomena: (a) activation of pyruvate carboxylase by acetyl-CoA; (b) acti-
vation of pyruvate dehydrogenase kinase by NADH; (c) inhibition of isoci-
trate dehydrogenase by NADH; (d) activation of isocitrate dehydrogenase by
ADP; (e) inhibition of a-ketoglutarate dehydrogenase by succinyl-CoA;
(f) activation of pyruvate dehydrogenase phosphatase by Ca*.
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Transcribed Image Text:. Briefly describe the biological rationale for cach of the following allosteric phenomena: (a) activation of pyruvate carboxylase by acetyl-CoA; (b) acti- vation of pyruvate dehydrogenase kinase by NADH; (c) inhibition of isoci- trate dehydrogenase by NADH; (d) activation of isocitrate dehydrogenase by ADP; (e) inhibition of a-ketoglutarate dehydrogenase by succinyl-CoA; (f) activation of pyruvate dehydrogenase phosphatase by Ca*.
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