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1. What are the three major pathways that eventually become entry points of molecules into the Krebs Cycle? Which molecules from these respective pathways are integrated into the Krebs Cycle?

1. What are the three major pathways that eventually become entry points of molecules into the Krebs Cycle? Which molecules from these respective pathways are integrated into the Krebs Cycle?

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Reread the case study carefully, make sure you understand it and to focus your attention when you reread the case study, make a note of any ideas that you think of. Answer the question linking relevant theories and concepts to specific information from the case study. Do not forget to include the question and use different sources and cite them properly (APA format). Use in- text citation and collate all the references at the end. 1. What are the three major pathways that eventually become entry points of molecules into the Krebs Cycle? Which molecules from these respective pathways are integrated into the Krebs Cycle? 2. How is a "committed step" defined in the context of a metabolic pathway and why are they important? Which steps and/or enzymes are involved in the committed steps in the Krebs Cycle? What are the possible implications of these steps were deregulated? 3. What are the three Krebs Cycle inborn errors mentioned in the paper? Why are they called deficiencies? What do you think are the probable causes for these? 4. In your own words, what do you think is/are the reason/s why most of the clinical features of these diseases involve muscle and nerve tissue? 5. Given the clinical manifestations, what suggestion do you have pertaining to the management of the diseases mentioned?
Transcribed Image Text:Reread the case study carefully, make sure you understand it and to focus your attention when you reread the case study, make a note of any ideas that you think of. Answer the question linking relevant theories and concepts to specific information from the case study. Do not forget to include the question and use different sources and cite them properly (APA format). Use in- text citation and collate all the references at the end. 1. What are the three major pathways that eventually become entry points of molecules into the Krebs Cycle? Which molecules from these respective pathways are integrated into the Krebs Cycle? 2. How is a "committed step" defined in the context of a metabolic pathway and why are they important? Which steps and/or enzymes are involved in the committed steps in the Krebs Cycle? What are the possible implications of these steps were deregulated? 3. What are the three Krebs Cycle inborn errors mentioned in the paper? Why are they called deficiencies? What do you think are the probable causes for these? 4. In your own words, what do you think is/are the reason/s why most of the clinical features of these diseases involve muscle and nerve tissue? 5. Given the clinical manifestations, what suggestion do you have pertaining to the management of the diseases mentioned?
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