Organic Chemistry
Organic Chemistry
6th Edition
ISBN: 9781936221349
Author: Marc Loudon, Jim Parise
Publisher: W. H. Freeman
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Chapter 10, Problem 10.63AP
Interpretation Introduction

(a)

Interpretation:

The products of the illustrated compound with fumarase in H2O applying the principle of microscopic reversibility is to be predicted.

Concept introduction:

The principle of microscopic reversibility states that if a reaction taking place in multiple steps is considered to be happening in equilibrium then the rate of forward and backward reaction becomes equal. That means the same reactants will be produced if the reaction is reversed using the same products.

Interpretation Introduction

(b)

Interpretation:

The products of the illustrated compound with fumarase in H2O applying the principle of microscopic reversibility is to be predicted.

Concept introduction:

The principle of microscopic reversibility states that if a reaction taking place in multiple steps is considered to be happening in equilibrium then the rate of forward and backward reaction becomes equal. That means the same reactants will be produced if the reaction is reversed using the same products.

Interpretation Introduction

(c)

Interpretation:

The products of the illustrated compound with fumarase in H2O applying the principle of microscopic reversibility is to be predicted.

Concept introduction:

The principle of microscopic reversibility states that if a reaction taking place in multiple steps is considered to be happening in equilibrium then the rate of forward and backward reaction becomes equal. That means the same reactants will be produced if the reaction is reversed using the same products.

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Carbonic anhydrase, an enzyme that converts carbon dioxide and water to carbonic acid as shown below, functions in the blood at an optimum pH of 7.0-7.5. Which of the following will lower the rate of carbonic anhydrase- catalyzed reaction? CO2 + H2O Carbonic anhydrase H₂CO3 O increasing the concentration of carbon dioxide O running the reaction at 4 °C carrying out the reaction at pH 7.2 O adding more carbonic anhydrase
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H NH₂ ཡིནྣཾ ༥ ཨ ཨནྡྷ༥ ༠ ཨི་ཝཱ, ཙ ཨ་ར༩ H NH3+ the acidity of the amine ion drives the reaction to shift toward the conjugate base of the carboxylic acid product. the resulting carboxylic acid ion is a weaker base than an acetate ion. O aldehydes are more reactive toward nucleophiles than ketones. Onucleophilic attack occurs preferentially at the less hindered carbon of the formyl group.

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