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Provide annotated structure image/diagram of the EPH RECEPTOR B2 (EPHB2).
Giving the ligand bidning sites.
Step by step
Solved in 2 steps with 1 images
- explain in detail ephrin receptor EPHB2 receptor interaction with PDZ ligand. give full step by step explanantion.name and describe the isoforms of the leptin receptor.what Protien ligand interacts the EPH RECEPTOR EPHB2 and what drug binds to the receptor. give example and Include details of bidning and signalling.
- Explain how mutations in the R or C subunit of cAMP-dependent protein kinase (PKA) might lead to (a) a constantly active PKA or (b) a constantly inactive PKA.Psilocybin is rapidly de-phosphorylated in the body into psilocin, which is anagonist For the 5-HT 2A Serotonin receptor, which binds the neurotransmitter serotonin as its natural ligand, and acts as a ligand-gated ion channel in the central nervous system. HO. Serotonin (a) Part of the sequence of the 5-HT 24 Receptor is NH₂ ...RQKACKVIGIVFFLFVVMWLAFFITNICDES... Identify the trans-membrane region within this sequence. Do you predict this sequence will Be transmembrane a-Helix or ß sheet? Why? (b) What is the distance spanned by this transmembrane region?Identify the structure highlighted in green: Epinephrine receptor ACh receptor Norepinephrine receptor
- Name two second messengers of GPCRs and identify the type of GPCR each second messenger commonly associates with (Gs, Gi, Gq, G12/13, Go; there are many possible answers for this question).Identify at least three key actions of epinephrine that render this agent beneficial for treating severe allergic reactions.Three potential inhibitors for VEGF were discussed in the signal transduction simulation. Explain two possible steps that these drugs can be expected to interfere with VEGF signaling (Hint: think about the requirements for signaling to occur).
